Sitagliptin phosphate: isolation and identification of two degradation products formed under acid conditions and determination of in vitro cytotoxicity

Sitagliptin phosphate: isolation and identification of two degradation products formed under acid conditions and determination of in vitro cytotoxicity

Sitagliptin phosphate (STG), used for the treatment of type 2 diabetes, is a drug that belongs to a new class called inhibitors of dipeptidyl peptidase IV (DPPIV). It is known to be the first agent of the class approved by the FDA. Currently, many studies describe the determination of STG in plasma...

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Bibliographic Details
Main Authors: Alini Dall Cortivo Lange, Diogo Miron, Le´tícia Lenz Sfair, Elfrides Eva Scherman Schapoval
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2023-07-01
Series:Drug Analytical Research
Subjects:
Sitagliptin phosphate
Indicating stability method
Degradation product]
Cytotoxicity.
Online Access:https://seer.ufrgs.br/index.php/dar/article/view/133259

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