Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review
Acute acalculous cholecystitis (AAC) represents cholecystitis without gallstones, occurring in approximately 5–10% of all cases of acute cholecystitis in adults. Several risk factors have been recognized, while infectious diseases can be a cause of cholecystitis in otherwise healthy people. Coronavi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/16/3/455 |
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| author | Evanthia Thomaidou Eleni Karlafti Matthaios Didagelos Kalliopi Megari Eleni Argiriadou Karolina Akinosoglou Daniel Paramythiotis Christos Savopoulos |
| author_facet | Evanthia Thomaidou Eleni Karlafti Matthaios Didagelos Kalliopi Megari Eleni Argiriadou Karolina Akinosoglou Daniel Paramythiotis Christos Savopoulos |
| author_sort | Evanthia Thomaidou |
| collection | DOAJ |
| description | Acute acalculous cholecystitis (AAC) represents cholecystitis without gallstones, occurring in approximately 5–10% of all cases of acute cholecystitis in adults. Several risk factors have been recognized, while infectious diseases can be a cause of cholecystitis in otherwise healthy people. Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has spread worldwide, leading to an unprecedented pandemic. The virus enters cells through the binding of the spike protein to angiotensin-converting enzyme 2 (ACE2) receptors expressed in many human tissues, including the epithelial cells of the gastrointestinal (GI) tract, and this explains the symptoms emanating from the digestive system. Acute cholecystitis has been reported in patients with COVID-19. The purpose of this review is to provide a detailed analysis of the current literature on the pathogenesis, diagnosis, management, and outcomes of AAC in patients with COVID-19. |
| first_indexed | 2024-04-24T17:45:06Z |
| format | Article |
| id | doaj.art-7819c13a77cc478d9cb2d756a02ae9b3 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-04-24T17:45:06Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-7819c13a77cc478d9cb2d756a02ae9b32024-03-27T14:07:56ZengMDPI AGViruses1999-49152024-03-0116345510.3390/v16030455Acalculous Cholecystitis in COVID-19 Patients: A Narrative ReviewEvanthia Thomaidou0Eleni Karlafti1Matthaios Didagelos2Kalliopi Megari3Eleni Argiriadou4Karolina Akinosoglou5Daniel Paramythiotis6Christos Savopoulos7Department of Anesthesiology and Intensive Care Unit, AHEPA University General Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceEmergency Department, AHEPA University General Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceDepartment of Anesthesiology and Intensive Care Unit, AHEPA University General Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceCITY College, University of York Europe Campus, 54626 Thessaloniki, GreeceDepartment of Anesthesiology and Intensive Care Unit, AHEPA University General Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceDepartment of Medicine, University General Hospital of Patras, 26504 Rio, GreeceFirst Propaedeutic Department of Surgery, AHEPA University General Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceFirst Propaedeutic Internal Medicine Department, AHEPA University General Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceAcute acalculous cholecystitis (AAC) represents cholecystitis without gallstones, occurring in approximately 5–10% of all cases of acute cholecystitis in adults. Several risk factors have been recognized, while infectious diseases can be a cause of cholecystitis in otherwise healthy people. Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has spread worldwide, leading to an unprecedented pandemic. The virus enters cells through the binding of the spike protein to angiotensin-converting enzyme 2 (ACE2) receptors expressed in many human tissues, including the epithelial cells of the gastrointestinal (GI) tract, and this explains the symptoms emanating from the digestive system. Acute cholecystitis has been reported in patients with COVID-19. The purpose of this review is to provide a detailed analysis of the current literature on the pathogenesis, diagnosis, management, and outcomes of AAC in patients with COVID-19.https://www.mdpi.com/1999-4915/16/3/455acalculous cholecystitisgallbladderCOVIDSARS-CoV-2 |
| spellingShingle | Evanthia Thomaidou Eleni Karlafti Matthaios Didagelos Kalliopi Megari Eleni Argiriadou Karolina Akinosoglou Daniel Paramythiotis Christos Savopoulos Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review Viruses acalculous cholecystitis gallbladder COVID SARS-CoV-2 |
| title | Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review |
| title_full | Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review |
| title_fullStr | Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review |
| title_full_unstemmed | Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review |
| title_short | Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review |
| title_sort | acalculous cholecystitis in covid 19 patients a narrative review |
| topic | acalculous cholecystitis gallbladder COVID SARS-CoV-2 |
| url | https://www.mdpi.com/1999-4915/16/3/455 |
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