Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry
Background and objective: Management of outpatients with stable coronary artery disease (CAD) is important in secondary prevention. The objective was to describe differences in the characteristics of CAD patients in Latvia compared with other countries. Materials and methods: CLARIFY is an ongoing i...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-01-01
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| Series: | Medicina |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1010660X15000555 |
| _version_ | 1797719504721018880 |
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| author | Andrejs Erglis Iveta Mintale Gustavs Latkovskis Inga Balode Sanda Jegere Iveta Bajare Aldis Rozenbergs Nicola Greenlaw Roberto Ferrari Philippe Gabriel Steg |
| author_facet | Andrejs Erglis Iveta Mintale Gustavs Latkovskis Inga Balode Sanda Jegere Iveta Bajare Aldis Rozenbergs Nicola Greenlaw Roberto Ferrari Philippe Gabriel Steg |
| author_sort | Andrejs Erglis |
| collection | DOAJ |
| description | Background and objective: Management of outpatients with stable coronary artery disease (CAD) is important in secondary prevention. The objective was to describe differences in the characteristics of CAD patients in Latvia compared with other countries.
Materials and methods: CLARIFY is an ongoing international, prospective, observational, longitudinal registry of outpatients with CAD. Data regarding treated outpatients with established CAD from the CLARIFY registry in Latvia (n = 120) were compared with those from the rest of Central-Eastern Europe (CEE) (n = 2888) and worldwide (n = 33,163).
Results: Patients in Latvia had a larger waist circumference (101 [95–109] vs. 99 [91–106] in CEE, 96.5 [88–105] cm worldwide; P = 0.023 and P < 0.001, respectively) and higher blood pressure (systolic: 138.28 ± 17.13 vs. 133.77 ± 16.47 in CEE and 130.97 ± 16.65 mm Hg worldwide, P = 0.003 and P < 0.001; diastolic: 82.98 ± 8.58 vs. 80.01 ± 9.61 in CEE and 77.22 ± 9.97 mm Hg worldwide, P < 0.001 and P < 0.001, respectively). Body mass index in Latvia did not differ significantly from that in CEE (P = 0.422), but was higher than worldwide (28.8 [26.2–32.0] vs. worldwide 27.3 [24.8–30.3] kg/m2, P < 0.001). The history of percutaneous coronary intervention was more frequent in Latvia (74.17% vs. 59.34% in CEE and 58.61% worldwide, P = 0.001 and P < 0.001, respectively). Latvian patients more frequently used aspirin (97.50% in Latvia vs. 89.75% in CEE and 87.64% worldwide, P = 0.005 and P = 0.001, respectively).
Conclusions: Latvian CAD patients are well managed in terms of aspirin use and frequency of percutaneous coronary intervention. Control of obesity and high BP is poorer and needs further improvement. |
| first_indexed | 2024-03-12T09:05:51Z |
| format | Article |
| id | doaj.art-7819cab6e6a3497dbcd2675cdcc963c8 |
| institution | Directory Open Access Journal |
| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T09:05:51Z |
| publishDate | 2015-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-7819cab6e6a3497dbcd2675cdcc963c82023-09-02T15:17:43ZengMDPI AGMedicina1010-660X2015-01-0151424024610.1016/j.medici.2015.05.004Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registryAndrejs Erglis0Iveta Mintale1Gustavs Latkovskis2Inga Balode3Sanda Jegere4Iveta Bajare5Aldis Rozenbergs6Nicola Greenlaw7Roberto Ferrari8Philippe Gabriel Steg9Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, LatviaLatvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, LatviaLatvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, LatviaRiga Stradins University, Riga, LatviaLatvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, LatviaResearch Institute of Cardiology, University of Latvia, Riga, LatviaResearch Institute of Cardiology, University of Latvia, Riga, LatviaRobertson Centre of Biostatistics, University of Glasgow, Glasgow, United KingdomDepartment of Cardiology and LTTA Centre, University Hospital of Ferrara and Maria Cecilia Hospital, GVM Care & Research, E.S. Health Science Foundation, Cotignola, ItalyINSERM U-1148 and University Paris Diderot, Paris, FranceBackground and objective: Management of outpatients with stable coronary artery disease (CAD) is important in secondary prevention. The objective was to describe differences in the characteristics of CAD patients in Latvia compared with other countries. Materials and methods: CLARIFY is an ongoing international, prospective, observational, longitudinal registry of outpatients with CAD. Data regarding treated outpatients with established CAD from the CLARIFY registry in Latvia (n = 120) were compared with those from the rest of Central-Eastern Europe (CEE) (n = 2888) and worldwide (n = 33,163). Results: Patients in Latvia had a larger waist circumference (101 [95–109] vs. 99 [91–106] in CEE, 96.5 [88–105] cm worldwide; P = 0.023 and P < 0.001, respectively) and higher blood pressure (systolic: 138.28 ± 17.13 vs. 133.77 ± 16.47 in CEE and 130.97 ± 16.65 mm Hg worldwide, P = 0.003 and P < 0.001; diastolic: 82.98 ± 8.58 vs. 80.01 ± 9.61 in CEE and 77.22 ± 9.97 mm Hg worldwide, P < 0.001 and P < 0.001, respectively). Body mass index in Latvia did not differ significantly from that in CEE (P = 0.422), but was higher than worldwide (28.8 [26.2–32.0] vs. worldwide 27.3 [24.8–30.3] kg/m2, P < 0.001). The history of percutaneous coronary intervention was more frequent in Latvia (74.17% vs. 59.34% in CEE and 58.61% worldwide, P = 0.001 and P < 0.001, respectively). Latvian patients more frequently used aspirin (97.50% in Latvia vs. 89.75% in CEE and 87.64% worldwide, P = 0.005 and P = 0.001, respectively). Conclusions: Latvian CAD patients are well managed in terms of aspirin use and frequency of percutaneous coronary intervention. Control of obesity and high BP is poorer and needs further improvement.http://www.sciencedirect.com/science/article/pii/S1010660X15000555Coronary artery diseaseLatviaRisk factorsPrevention |
| spellingShingle | Andrejs Erglis Iveta Mintale Gustavs Latkovskis Inga Balode Sanda Jegere Iveta Bajare Aldis Rozenbergs Nicola Greenlaw Roberto Ferrari Philippe Gabriel Steg Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry Medicina Coronary artery disease Latvia Risk factors Prevention |
| title | Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry |
| title_full | Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry |
| title_fullStr | Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry |
| title_full_unstemmed | Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry |
| title_short | Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry |
| title_sort | management of coronary artery disease patients in latvia compared with practice in central eastern europe and globally analysis of the clarify registry |
| topic | Coronary artery disease Latvia Risk factors Prevention |
| url | http://www.sciencedirect.com/science/article/pii/S1010660X15000555 |
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