Suppression of TGFβ-Induced Interleukin-6 Secretion by Sinulariolide from Soft Corals through Attenuation of the p38–NF-kB Pathway in Carcinoma Cells

Suppression of TGFβ-Induced Interleukin-6 Secretion by Sinulariolide from Soft Corals through Attenuation of the p38–NF-kB Pathway in Carcinoma Cells

Sinulariolide (SC-1) is a natural product extracted from the cultured-type soft coral <i>Sinularia flexibilis</i> and possesses anti-inflammation, anti-proliferative, and anti-migratory in several types of cancer cells. However, the molecular pathway behind its effects on inflammation re...

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Bibliographic Details
Main Authors: Jenq-Lin Yang, Weng-Ling Lin, Shun-Ban Tai, Yi-Siang Ciou, Chih-Ling Chung, Jih-Jung Chen, Pei-Feng Liu, Ming-Wei Lin, Chun-Lin Chen
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
sinulariolide
TGF-β
interleukin-6
Online Access:https://www.mdpi.com/1422-0067/24/14/11656

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