<b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876

Nowadays, there is a great interest in the research and the production of functional foods, such as isoflavones. Which present proven action on the prevention of health problems, such as cancer and cardiovascular diseases. Considering the importance of soybean supplements standardization, this study...

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Main Authors: Daniel Mantovani, Lúcio Cardozo Filho, Leonilda Correia Santos, Vera Lúcia Ferreira de Souza, Cecilia Sumie Watanabe
Format: Article
Language:English
Published: Universidade Estadual de Maringá 2011-02-01
Series:Acta Scientiarum: Biological Sciences
Subjects:
Online Access:https://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6876
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author Daniel Mantovani
Lúcio Cardozo Filho
Leonilda Correia Santos
Vera Lúcia Ferreira de Souza
Cecilia Sumie Watanabe
author_facet Daniel Mantovani
Lúcio Cardozo Filho
Leonilda Correia Santos
Vera Lúcia Ferreira de Souza
Cecilia Sumie Watanabe
author_sort Daniel Mantovani
collection DOAJ
description Nowadays, there is a great interest in the research and the production of functional foods, such as isoflavones. Which present proven action on the prevention of health problems, such as cancer and cardiovascular diseases. Considering the importance of soybean supplements standardization, this study aimed identifying and quantifying the isoflavones in products sold at different pharmacies. Isoflavones samples were acquired in six different pharmacies specialized in the production of phytotherapic medications. The isoflavones were extracted, quantified and identified in HPLC. None of the samples, from different pharmacies, presented the isoflavones content presented on the label, i.e., 20 mg. In relation to the isoflavones profile, the highest levels found were of daidzein, with up to 66.8 ± 0.09 µg, being the lowest levels the ones of genistein. It is necessary, therefore, the adoption of methods for the standardization and characterization of the raw materials used by different pharmacies. It would assure the isoflavones content, once they are essential for the effects prescribed by the professionals in the medical area.
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spelling doaj.art-781d8b7edef642749d528d4d3822ee8e2022-12-22T03:37:12ZengUniversidade Estadual de MaringáActa Scientiarum: Biological Sciences1679-92831807-863X2011-02-0133110.4025/actascibiolsci.v33i1.6876<b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876Daniel Mantovani0Lúcio Cardozo Filho1Leonilda Correia Santos2Vera Lúcia Ferreira de Souza3Cecilia Sumie Watanabe4Universidade Federal do ParanáUniversidade Estadual de MaringáUnversidade Estadual do Oeste do ParanáUniversidade Estadual de MaringáUniversidade Estadual de MaringáNowadays, there is a great interest in the research and the production of functional foods, such as isoflavones. Which present proven action on the prevention of health problems, such as cancer and cardiovascular diseases. Considering the importance of soybean supplements standardization, this study aimed identifying and quantifying the isoflavones in products sold at different pharmacies. Isoflavones samples were acquired in six different pharmacies specialized in the production of phytotherapic medications. The isoflavones were extracted, quantified and identified in HPLC. None of the samples, from different pharmacies, presented the isoflavones content presented on the label, i.e., 20 mg. In relation to the isoflavones profile, the highest levels found were of daidzein, with up to 66.8 ± 0.09 µg, being the lowest levels the ones of genistein. It is necessary, therefore, the adoption of methods for the standardization and characterization of the raw materials used by different pharmacies. It would assure the isoflavones content, once they are essential for the effects prescribed by the professionals in the medical area.https://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6876Daidzeingenisteinfunctional compoundssoybeanquantity
spellingShingle Daniel Mantovani
Lúcio Cardozo Filho
Leonilda Correia Santos
Vera Lúcia Ferreira de Souza
Cecilia Sumie Watanabe
<b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876
Acta Scientiarum: Biological Sciences
Daidzein
genistein
functional compounds
soybean
quantity
title <b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876
title_full <b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876
title_fullStr <b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876
title_full_unstemmed <b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876
title_short <b>The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies</b> - doi: 10.4025/actascibiolsci.v33i1.6876
title_sort b the use of hplc identification and quantification of isoflavones content in samples obtained in pharmacies b doi 10 4025 actascibiolsci v33i1 6876
topic Daidzein
genistein
functional compounds
soybean
quantity
url https://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6876
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