Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020
The aim of this study was to examine the incidence and mortality trends for tumors and cardiovascular disease (CVD) in a province of northern Italy. The study included kidney cancers recorded in the period 1996–2020, divided by sex, age, year of incidence and years from diagnosis. The standardized i...
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| Format: | Article |
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MDPI AG
2022-07-01
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| Online Access: | https://www.mdpi.com/2079-7737/11/7/1048 |
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| author | Lucia Mangone Francesco Marinelli Luigi Tarantini Cristina Masini Alessandro Navazio Stefania Di Girolamo Isabella Bisceglia Carmine Pinto |
| author_facet | Lucia Mangone Francesco Marinelli Luigi Tarantini Cristina Masini Alessandro Navazio Stefania Di Girolamo Isabella Bisceglia Carmine Pinto |
| author_sort | Lucia Mangone |
| collection | DOAJ |
| description | The aim of this study was to examine the incidence and mortality trends for tumors and cardiovascular disease (CVD) in a province of northern Italy. The study included kidney cancers recorded in the period 1996–2020, divided by sex, age, year of incidence and years from diagnosis. The standardized incidence rate was calculated using the European population, and the Annual Percent Change (APC) was reported. In total, 2331 patients with kidney cancers were identified, mainly males (1504 cases) aged 60–79 years (1240 cases). There were 1257 deaths; there were no differences according sex but there were differences according to age (12.1% among younger adults and 80.4% among 80+). The incidence rate increased in males between 1996 and 2011 (APC = 2.3), while the mortality rate decreased in both males (APC = −3.3%) and females (APC = −4.5%). Comparing the same periods, kidney cancer-specific mortality decreased from 81.8% to 43.7%, while in the same period there was an increasing trend for CVD mortality. Moreover, the risk of CVD mortality increased as we moved away from the diagnosis (from 6.2% to 27.5%, <i>p</i> < 0.01). The same trend was observed for other causes of death (from 12.6% to 32.1%, <i>p</i> < 0.01). Thus, a multidisciplinary approach seems necessary during the follow-up and treatments of patients with kidney cancer. |
| first_indexed | 2024-03-09T12:13:53Z |
| format | Article |
| id | doaj.art-781ea33573a0427685f0949ec8476eba |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-09T12:13:53Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-781ea33573a0427685f0949ec8476eba2023-11-30T22:49:23ZengMDPI AGBiology2079-77372022-07-01117104810.3390/biology11071048Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020Lucia Mangone0Francesco Marinelli1Luigi Tarantini2Cristina Masini3Alessandro Navazio4Stefania Di Girolamo5Isabella Bisceglia6Carmine Pinto7Epidemiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Via Amendola 2, 42122 Reggio Emilia, ItalyEpidemiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Via Amendola 2, 42122 Reggio Emilia, ItalyCardiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyMedical Oncology Unit, Comprehensive Cancer Centre, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyCardiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyMedical Oncology Unit, Comprehensive Cancer Centre, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyEpidemiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Via Amendola 2, 42122 Reggio Emilia, ItalyMedical Oncology Unit, Comprehensive Cancer Centre, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, ItalyThe aim of this study was to examine the incidence and mortality trends for tumors and cardiovascular disease (CVD) in a province of northern Italy. The study included kidney cancers recorded in the period 1996–2020, divided by sex, age, year of incidence and years from diagnosis. The standardized incidence rate was calculated using the European population, and the Annual Percent Change (APC) was reported. In total, 2331 patients with kidney cancers were identified, mainly males (1504 cases) aged 60–79 years (1240 cases). There were 1257 deaths; there were no differences according sex but there were differences according to age (12.1% among younger adults and 80.4% among 80+). The incidence rate increased in males between 1996 and 2011 (APC = 2.3), while the mortality rate decreased in both males (APC = −3.3%) and females (APC = −4.5%). Comparing the same periods, kidney cancer-specific mortality decreased from 81.8% to 43.7%, while in the same period there was an increasing trend for CVD mortality. Moreover, the risk of CVD mortality increased as we moved away from the diagnosis (from 6.2% to 27.5%, <i>p</i> < 0.01). The same trend was observed for other causes of death (from 12.6% to 32.1%, <i>p</i> < 0.01). Thus, a multidisciplinary approach seems necessary during the follow-up and treatments of patients with kidney cancer.https://www.mdpi.com/2079-7737/11/7/1048kidney cancertrendsincidencemortalitycancer registryrenal cell carcinoma |
| spellingShingle | Lucia Mangone Francesco Marinelli Luigi Tarantini Cristina Masini Alessandro Navazio Stefania Di Girolamo Isabella Bisceglia Carmine Pinto Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020 Biology kidney cancer trends incidence mortality cancer registry renal cell carcinoma |
| title | Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020 |
| title_full | Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020 |
| title_fullStr | Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020 |
| title_full_unstemmed | Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020 |
| title_short | Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020 |
| title_sort | trends in incidence and mortality of kidney cancer in a northern italian province an update to 2020 |
| topic | kidney cancer trends incidence mortality cancer registry renal cell carcinoma |
| url | https://www.mdpi.com/2079-7737/11/7/1048 |
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