Hair follicle stem cells and mitochondria

Hair is a skin appendage that protects the skin from external factors such as physical stimuli, temperature changes, and ultraviolet light. Since hair also plays an important role aesthetically, many people are interested in hair growth and loss. Hair growth is a complex process, which is finely reg...

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Main Author: Chang-Deok Kim
Format: Article
Language:English
Published: Korean Society of Korean Cosmetic Surgery and medicine 2023-06-01
Series:Journal of Cosmetic Medicine
Subjects:
Online Access:http://www.jcosmetmed.org/journal/view.html?doi=10.25056/JCM.2023.7.1.6
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author Chang-Deok Kim
author_facet Chang-Deok Kim
author_sort Chang-Deok Kim
collection DOAJ
description Hair is a skin appendage that protects the skin from external factors such as physical stimuli, temperature changes, and ultraviolet light. Since hair also plays an important role aesthetically, many people are interested in hair growth and loss. Hair growth is a complex process, which is finely regulated by interactions between the various cells that make up the hair follicle. In particular, hair follicle stem cells are present in the bulge area of the hair follicle and since these cells can differentiate into various cells constituting the hair follicle, they play a pivotal role in maintaining the hair growth cycle. Hair follicle stem cells usually remain quiescent, but under certain circumstances, they become activated, start dividing, and migrate to the lower part of the bulge to form anagen hair follicle. Along with many genes involved in the process of quiescence and activation of hair follicle stem cells, energy metabolism can also affect hair follicle stem cell activity. In this regard, the role of mitochondria, energy-generating organelles, in hair follicle stem cells should be emphasized.
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spelling doaj.art-7826036214ae48d1a78944a5814de01f2023-06-30T11:11:44ZengKorean Society of Korean Cosmetic Surgery and medicineJournal of Cosmetic Medicine2508-88312023-06-01716810.25056/JCM.2023.7.1.6JCM.2023.7.1.6Hair follicle stem cells and mitochondriaChang-Deok Kim0Department of Dermatology, Chungnam National University College of Medicine, Daejeon, Rep. of KoreaHair is a skin appendage that protects the skin from external factors such as physical stimuli, temperature changes, and ultraviolet light. Since hair also plays an important role aesthetically, many people are interested in hair growth and loss. Hair growth is a complex process, which is finely regulated by interactions between the various cells that make up the hair follicle. In particular, hair follicle stem cells are present in the bulge area of the hair follicle and since these cells can differentiate into various cells constituting the hair follicle, they play a pivotal role in maintaining the hair growth cycle. Hair follicle stem cells usually remain quiescent, but under certain circumstances, they become activated, start dividing, and migrate to the lower part of the bulge to form anagen hair follicle. Along with many genes involved in the process of quiescence and activation of hair follicle stem cells, energy metabolism can also affect hair follicle stem cell activity. In this regard, the role of mitochondria, energy-generating organelles, in hair follicle stem cells should be emphasized.http://www.jcosmetmed.org/journal/view.html?doi=10.25056/JCM.2023.7.1.6energy metabolism; hair follicle stem cells; mitochondria
spellingShingle Chang-Deok Kim
Hair follicle stem cells and mitochondria
Journal of Cosmetic Medicine
energy metabolism; hair follicle stem cells; mitochondria
title Hair follicle stem cells and mitochondria
title_full Hair follicle stem cells and mitochondria
title_fullStr Hair follicle stem cells and mitochondria
title_full_unstemmed Hair follicle stem cells and mitochondria
title_short Hair follicle stem cells and mitochondria
title_sort hair follicle stem cells and mitochondria
topic energy metabolism; hair follicle stem cells; mitochondria
url http://www.jcosmetmed.org/journal/view.html?doi=10.25056/JCM.2023.7.1.6
work_keys_str_mv AT changdeokkim hairfolliclestemcellsandmitochondria