Tumor cell-derived asymmetric dimethylarginine regulates macrophage functions and polarization
Abstract Background Asymmetric dimethylarginine (ADMA), which is significantly elevated in the plasma of cancer patients, is formed via intracellular recycling of methylated proteins and serves as a precursor for resynthesis of arginine. However, the cause of ADMA elevation in cancers and its impact...
Main Authors: | Yi-Ling Chen, AKaychia T. Lowery, Samuel Lin, Ameae M. Walker, Kuan-Hui E. Chen |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-022-02769-7 |
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