miR-454-3p and miR-194-5p targeting cardiac sarcolemma ion exchange transcripts are potential noninvasive diagnostic biomarkers for childhood dilated cardiomyopathy in Egyptian patients

miR-454-3p and miR-194-5p targeting cardiac sarcolemma ion exchange transcripts are potential noninvasive diagnostic biomarkers for childhood dilated cardiomyopathy in Egyptian patients

Abstract Background Childhood dilated cardiomyopathy (CDCM) is the most common cardiomyopathy in children and it is risk factor to heart failure and sudden death. Most of the different etiologic factors which have been postulated to DCM are idiopathic, and its pathogenesis remains uncertain. So it w...

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Bibliographic Details
Main Authors: Alaaeldin G. Fayez, Nora N. Esmaiel, Sohair M. Salem, Engy A. Ashaat, Sonia A. El-Saiedi, Mona O. El Ruby
Format: Article
Language:English
Published: SpringerOpen 2022-09-01
Series:The Egyptian Heart Journal
Subjects:
Childhood dilated cardiomyopathy
Noninvasive diagnostic biomarkers
miRNAs
Cardiac sarcolemma
Gene ontology analysis
Online Access:https://doi.org/10.1186/s43044-022-00300-x

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