Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints

Numerous non-surgical and surgical procedures have been proposed to treat injuries and diseases of the large joints. Any small bone and cartilage defect can progress quite quickly and cause osteoarthritis to develop in many joints without proper treatment. Surgical procedures include tunnelization,...

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Main Author: G. A. Airapetov
Format: Article
Language:Russian
Published: Remedium Group LLC 2019-03-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/2903
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author G. A. Airapetov
author_facet G. A. Airapetov
author_sort G. A. Airapetov
collection DOAJ
description Numerous non-surgical and surgical procedures have been proposed to treat injuries and diseases of the large joints. Any small bone and cartilage defect can progress quite quickly and cause osteoarthritis to develop in many joints without proper treatment. Surgical procedures include tunnelization, microfracturing, mosaic autochondroplasty, etc. The joint condition can be improved by using exogenous growth factors. Platelet-rich plasma (PRP) is one of the remedies that contain regeneration-stimulating factors. The article discusses the positive effects of PRP not only on chondrogenesis in the area of hyaline cartilage defects, but also on osteoarthritis. There is a need to further clarify the mechanism of action of plasma and the exact concentration of the preparation.
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spelling doaj.art-782bb8b8ad304f0aada1fef6913617362023-04-23T06:56:49ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902019-03-0101848710.21518/2079-701X-2019-1-84-872827Therapeutic potential of platelet-rich plasma in diseases and injuries of the large jointsG. A. Airapetov0Federal State Budgetary Educational Institution of Higher Education «Stavropol State Medical University» of the Ministry of Health of the Russian FederationNumerous non-surgical and surgical procedures have been proposed to treat injuries and diseases of the large joints. Any small bone and cartilage defect can progress quite quickly and cause osteoarthritis to develop in many joints without proper treatment. Surgical procedures include tunnelization, microfracturing, mosaic autochondroplasty, etc. The joint condition can be improved by using exogenous growth factors. Platelet-rich plasma (PRP) is one of the remedies that contain regeneration-stimulating factors. The article discusses the positive effects of PRP not only on chondrogenesis in the area of hyaline cartilage defects, but also on osteoarthritis. There is a need to further clarify the mechanism of action of plasma and the exact concentration of the preparation.https://www.med-sovet.pro/jour/article/view/2903bone and cartilage defectsregenerationplasmaprposteoarthritis
spellingShingle G. A. Airapetov
Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints
Медицинский совет
bone and cartilage defects
regeneration
plasma
prp
osteoarthritis
title Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints
title_full Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints
title_fullStr Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints
title_full_unstemmed Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints
title_short Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints
title_sort therapeutic potential of platelet rich plasma in diseases and injuries of the large joints
topic bone and cartilage defects
regeneration
plasma
prp
osteoarthritis
url https://www.med-sovet.pro/jour/article/view/2903
work_keys_str_mv AT gaairapetov therapeuticpotentialofplateletrichplasmaindiseasesandinjuriesofthelargejoints