New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen
In this study, a green ionic-liquid based vortex-synchronized matrix solid-phase dispersion (VS-MSPD) combined with high performance liquid chromatography (HPLC) method was developed as a quantitative determination method for four anthraquinones in Cassiae Semen. Two conventional adsorbents, C<su...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-04-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/24/7/1312 |
| _version_ | 1819205187555819520 |
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| author | Luyi Jiang Jie Wang Huan Zhang Caijing Liu Yiping Tang Chu Chu |
| author_facet | Luyi Jiang Jie Wang Huan Zhang Caijing Liu Yiping Tang Chu Chu |
| author_sort | Luyi Jiang |
| collection | DOAJ |
| description | In this study, a green ionic-liquid based vortex-synchronized matrix solid-phase dispersion (VS-MSPD) combined with high performance liquid chromatography (HPLC) method was developed as a quantitative determination method for four anthraquinones in Cassiae Semen. Two conventional adsorbents, C<sub>18</sub> and silica gel were investigated. The strategy included two steps: Extraction and determination. Wasted crab shells were used as an alternative adsorbent and ionic liquid was used as an alternative solvent in the first step. Factors affecting extraction efficiency were optimized: A sample/adsorbent ratio of 2:1, a grinding time of 3 min, a vortex time of 3 min, and ionic liquid ([Domim]HSO<sub>4</sub>, 250 mM) was used as eluent in the VS-MSPD procedure. As a result, the established method provided satisfactory linearity (R > 0.999), good accuracy and high reproducibility (RSD < 4.60%), and it exhibited the advantages of smaller sample amounts, shorter extraction time, less volume of elution solvent, and was much more environmental-friendly when compared with other conventional methods. |
| first_indexed | 2024-12-23T04:47:43Z |
| format | Article |
| id | doaj.art-782c9ab46dfb413ea8741be9b3d3af8a |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-23T04:47:43Z |
| publishDate | 2019-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-782c9ab46dfb413ea8741be9b3d3af8a2022-12-21T17:59:35ZengMDPI AGMolecules1420-30492019-04-01247131210.3390/molecules24071312molecules24071312New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae SemenLuyi Jiang0Jie Wang1Huan Zhang2Caijing Liu3Yiping Tang4Chu Chu5College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, ChinaCollege of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310014, ChinaCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, ChinaCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, ChinaCollege of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310014, ChinaCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, ChinaIn this study, a green ionic-liquid based vortex-synchronized matrix solid-phase dispersion (VS-MSPD) combined with high performance liquid chromatography (HPLC) method was developed as a quantitative determination method for four anthraquinones in Cassiae Semen. Two conventional adsorbents, C<sub>18</sub> and silica gel were investigated. The strategy included two steps: Extraction and determination. Wasted crab shells were used as an alternative adsorbent and ionic liquid was used as an alternative solvent in the first step. Factors affecting extraction efficiency were optimized: A sample/adsorbent ratio of 2:1, a grinding time of 3 min, a vortex time of 3 min, and ionic liquid ([Domim]HSO<sub>4</sub>, 250 mM) was used as eluent in the VS-MSPD procedure. As a result, the established method provided satisfactory linearity (R > 0.999), good accuracy and high reproducibility (RSD < 4.60%), and it exhibited the advantages of smaller sample amounts, shorter extraction time, less volume of elution solvent, and was much more environmental-friendly when compared with other conventional methods.https://www.mdpi.com/1420-3049/24/7/1312vortex-synchronized matrix solid-phase dispersioncrab shellsionic liquidsanthraquinonesCassiae Semen |
| spellingShingle | Luyi Jiang Jie Wang Huan Zhang Caijing Liu Yiping Tang Chu Chu New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen Molecules vortex-synchronized matrix solid-phase dispersion crab shells ionic liquids anthraquinones Cassiae Semen |
| title | New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen |
| title_full | New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen |
| title_fullStr | New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen |
| title_full_unstemmed | New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen |
| title_short | New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen |
| title_sort | new vortex synchronized matrix solid phase dispersion method for simultaneous determination of four anthraquinones in cassiae semen |
| topic | vortex-synchronized matrix solid-phase dispersion crab shells ionic liquids anthraquinones Cassiae Semen |
| url | https://www.mdpi.com/1420-3049/24/7/1312 |
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