Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trial

Introduction A disturbance in exercise-induced hypoalgesia (EIH) has been observed in patients with chronic whiplash-associated disorders (WAD). Yet, no studies have examined whether EIH occurs in people with acute/subacute WAD. This study will determine whether EIH occurs immediately after and 24 h...

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Main Authors: Deborah Falla, Ernesto Anarte-Lazo, Carlos Bernal-Utrera, Mario Lopez-Amor, Eugenia Porras-Valencia, Francisco Javier Ruy-Diaz-Rojas, Cleofas Rodriguez-Blanco
Format: Article
Language:English
Published: BMJ Publishing Group 2022-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/9/e061679.full
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author Deborah Falla
Ernesto Anarte-Lazo
Carlos Bernal-Utrera
Mario Lopez-Amor
Eugenia Porras-Valencia
Francisco Javier Ruy-Diaz-Rojas
Cleofas Rodriguez-Blanco
author_facet Deborah Falla
Ernesto Anarte-Lazo
Carlos Bernal-Utrera
Mario Lopez-Amor
Eugenia Porras-Valencia
Francisco Javier Ruy-Diaz-Rojas
Cleofas Rodriguez-Blanco
author_sort Deborah Falla
collection DOAJ
description Introduction A disturbance in exercise-induced hypoalgesia (EIH) has been observed in patients with chronic whiplash-associated disorders (WAD). Yet, no studies have examined whether EIH occurs in people with acute/subacute WAD. This study will determine whether EIH occurs immediately after and 24 hours after aerobic exercise (AE) and neck-specific exercise (NSE) in people with acute/subacute WAD.Methods and analysis A randomised controlled trial has been designed and is reported in line with the Standard Protocol Items: Recommendations for Interventional Trials. EIH will be assessed immediately after and 24 hours after AE, NSE and a control intervention (randomly allocated). As dependent variables of the study, we will measure pressure pain thresholds measured over the region of the spinous process of C2 and C5, the muscle belly of the tibialis anterior and over the three main peripheral nerve trunks, Neck Pain Intensity, Neck-Disability Index, Pain Catastrophizing Scale, Tampa Scale Kinesiophobia-11, self-reported Leeds Assessment of Neuropathic Symptoms and Signs Scale.Ethics approval and dissemination Ethical approval has been granted by the Ethics Committee from University Rey Juan Carlos (Madrid, Spain; reference number 0707202116721). The results of this study will be disseminated through presentations at scientific conferences and publication in scientific journals.Trial registration number RBR-9tqr2jt, https://ensaiosclinicos.gov.br/observador/submissao/sumario/11551.
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spelling doaj.art-7838eaaea5194ce69d3a3f2abb8549f32022-12-22T03:37:11ZengBMJ Publishing GroupBMJ Open2044-60552022-09-0112910.1136/bmjopen-2022-061679Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trialDeborah Falla0Ernesto Anarte-Lazo1Carlos Bernal-Utrera2Mario Lopez-Amor3Eugenia Porras-Valencia4Francisco Javier Ruy-Diaz-Rojas5Cleofas Rodriguez-Blanco6Centre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UKCentre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UKDepartment of Physiotherapy, University of Seville, Sevilla, Andalucía, SpainDepartment of Physiotherapy, Clinica San Vicente, Madrid, SpainDepartment of Physiotherapy, Clinica San Vicente, Madrid, SpainDepartment of Physiotherapy, Clinica San Vicente, Madrid, SpainDepartment of Physiotherapy, University of Seville, Sevilla, Andalucía, SpainIntroduction A disturbance in exercise-induced hypoalgesia (EIH) has been observed in patients with chronic whiplash-associated disorders (WAD). Yet, no studies have examined whether EIH occurs in people with acute/subacute WAD. This study will determine whether EIH occurs immediately after and 24 hours after aerobic exercise (AE) and neck-specific exercise (NSE) in people with acute/subacute WAD.Methods and analysis A randomised controlled trial has been designed and is reported in line with the Standard Protocol Items: Recommendations for Interventional Trials. EIH will be assessed immediately after and 24 hours after AE, NSE and a control intervention (randomly allocated). As dependent variables of the study, we will measure pressure pain thresholds measured over the region of the spinous process of C2 and C5, the muscle belly of the tibialis anterior and over the three main peripheral nerve trunks, Neck Pain Intensity, Neck-Disability Index, Pain Catastrophizing Scale, Tampa Scale Kinesiophobia-11, self-reported Leeds Assessment of Neuropathic Symptoms and Signs Scale.Ethics approval and dissemination Ethical approval has been granted by the Ethics Committee from University Rey Juan Carlos (Madrid, Spain; reference number 0707202116721). The results of this study will be disseminated through presentations at scientific conferences and publication in scientific journals.Trial registration number RBR-9tqr2jt, https://ensaiosclinicos.gov.br/observador/submissao/sumario/11551.https://bmjopen.bmj.com/content/12/9/e061679.full
spellingShingle Deborah Falla
Ernesto Anarte-Lazo
Carlos Bernal-Utrera
Mario Lopez-Amor
Eugenia Porras-Valencia
Francisco Javier Ruy-Diaz-Rojas
Cleofas Rodriguez-Blanco
Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trial
BMJ Open
title Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trial
title_full Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trial
title_fullStr Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trial
title_full_unstemmed Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trial
title_short Exercise-induced hypoalgesia after aerobic versus neck-specific exercise in people with acute/subacute whiplash-associated disorders: protocol for a randomised controlled trial
title_sort exercise induced hypoalgesia after aerobic versus neck specific exercise in people with acute subacute whiplash associated disorders protocol for a randomised controlled trial
url https://bmjopen.bmj.com/content/12/9/e061679.full
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