Possible Application of Cytochrome b Gene for Human Identification
The mitochondrial cytochrome b gene (cytb) has been partially amplified and sequenced in order to identify the characteristic SNPs (single nucleotide polymorphism) for some Saudi Arabian tribes. Approximately 1 kbp from this gene has been sequenced and aligned with the same fragment of the revised C...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Arabic |
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Naif University Publishing House
2015-12-01
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| Series: | Arab Journal of Forensic Sciences & Forensic Medicine |
| Subjects: | |
| Online Access: | https://journals.nauss.edu.sa/index.php/AJFSFM/article/view/117 |
| _version_ | 1797265054051074048 |
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| author | Sayed A.M. Amer Bandar AlHothali Salah M. A. Tubaigy |
| author_facet | Sayed A.M. Amer Bandar AlHothali Salah M. A. Tubaigy |
| author_sort | Sayed A.M. Amer |
| collection | DOAJ |
| description | The mitochondrial cytochrome b gene (cytb) has been partially amplified and sequenced in order to identify the characteristic SNPs (single nucleotide polymorphism) for some Saudi Arabian tribes. Approximately 1 kbp from this gene has been sequenced and aligned with the same fragment of the revised Cambridge Reference Sequence (rCRS). The polymorphic sites and the haplotypes of all studied individuals were identified. Commonly, three main SNPs (G15301A, A15326G and T15674C) and 6 haplotypes (H, L, JT, U5a, R, J) were found. Most of the recorded SNPs and haplotypes were tribe dependant. Therefore, cytb gene could be considered as a powerful forensic marker; however, more samples must be analyzed to investigate the unique distribution for forensic applications. |
| first_indexed | 2024-04-25T00:38:41Z |
| format | Article |
| id | doaj.art-783a49e4cb5045eab04d9427c61926f7 |
| institution | Directory Open Access Journal |
| issn | 1658-6786 1658-6794 |
| language | Arabic |
| last_indexed | 2024-04-25T00:38:41Z |
| publishDate | 2015-12-01 |
| publisher | Naif University Publishing House |
| record_format | Article |
| series | Arab Journal of Forensic Sciences & Forensic Medicine |
| spelling | doaj.art-783a49e4cb5045eab04d9427c61926f72024-03-12T12:28:14ZaraNaif University Publishing HouseArab Journal of Forensic Sciences & Forensic Medicine1658-67861658-67942015-12-011210.12816/001770527Possible Application of Cytochrome b Gene for Human IdentificationSayed A.M. Amer0Bandar AlHothali1Salah M. A. Tubaigy2Biology Department, Faculty of Science, Taif UniversityCriminal evidence department, Ministry of InteriorForensic medicine, Ministry of Health, RiyadhThe mitochondrial cytochrome b gene (cytb) has been partially amplified and sequenced in order to identify the characteristic SNPs (single nucleotide polymorphism) for some Saudi Arabian tribes. Approximately 1 kbp from this gene has been sequenced and aligned with the same fragment of the revised Cambridge Reference Sequence (rCRS). The polymorphic sites and the haplotypes of all studied individuals were identified. Commonly, three main SNPs (G15301A, A15326G and T15674C) and 6 haplotypes (H, L, JT, U5a, R, J) were found. Most of the recorded SNPs and haplotypes were tribe dependant. Therefore, cytb gene could be considered as a powerful forensic marker; however, more samples must be analyzed to investigate the unique distribution for forensic applications.https://journals.nauss.edu.sa/index.php/AJFSFM/article/view/117mitochondrial dnasaudi tribessingle nucleotide polymorphism snpsforensic marker |
| spellingShingle | Sayed A.M. Amer Bandar AlHothali Salah M. A. Tubaigy Possible Application of Cytochrome b Gene for Human Identification Arab Journal of Forensic Sciences & Forensic Medicine mitochondrial dna saudi tribes single nucleotide polymorphism snps forensic marker |
| title | Possible Application of Cytochrome b Gene for Human Identification |
| title_full | Possible Application of Cytochrome b Gene for Human Identification |
| title_fullStr | Possible Application of Cytochrome b Gene for Human Identification |
| title_full_unstemmed | Possible Application of Cytochrome b Gene for Human Identification |
| title_short | Possible Application of Cytochrome b Gene for Human Identification |
| title_sort | possible application of cytochrome b gene for human identification |
| topic | mitochondrial dna saudi tribes single nucleotide polymorphism snps forensic marker |
| url | https://journals.nauss.edu.sa/index.php/AJFSFM/article/view/117 |
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