Investigating the Effect of Ibuprofen on DLL1 and NOTCH1 Expression in Gastric Cancer Stem Cells Derived from MKN-45 Cell Line

Investigating the Effect of Ibuprofen on DLL1 and NOTCH1 Expression in Gastric Cancer Stem Cells Derived from MKN-45 Cell Line

<strong>Background:</strong> Cancer stem cells (CSCs) harbor the self-renewal properties of the embryonic stem cells in addition to differentiation. While maintaining the balance between self-renewal and differentiation is required for homeostasis, dysregulation in the stem cell signalin...

Full description

Bibliographic Details
Main Authors:	Mohsen Farhangian, Frouzan Azarafrouz, Hossein Fallahi, Hassan Akrami
Format:	Article
Language:	English
Published:	Shiraz University of Medical Sciences 2019-10-01
Series:	Middle East Journal of Cancer
Subjects:	Notch signaling pathway Nonsteroidal anti-inflammatory drugs (NSAIDs) Gastric Cancer Cancer stem cells (CSCs)
Online Access:	http://mejc.sums.ac.ir/article_45542_91b01dde0c3db6840be07e8de4817854.pdf

Similar Items

MPDZ promotes DLL4-induced Notch signaling during angiogenesis
by: Fabian Tetzlaff, et al.
Published: (2018-04-01)

Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium
by: Ken-ichi Hirano, et al.
Published: (2022-03-01)

Concomitant Administration of Alprazolam and Ibuprofen in Acute Migraine Headache
by: M Baradaran, et al.
Published: (2011-05-01)

The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro
by: Lena Tveriakhina, et al.
Published: (2018-10-01)

Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways
by: Fokhrul Hossain, et al.
Published: (2018-12-01)

The Potential Preventive and Therapeutic Roles of NSAIDs in Prostate Cancer
by: Hossein Maghsoudi, et al.
Published: (2023-11-01)

Anti-metastatic Action of Non-steroidal Anti-inflammatory Drugs
by: Wen-Chun Hung
Published: (2008-08-01)

Rebamipide: New opportunities of gastroenteroprotection
by: V I Simanenkov, et al.
Published: (2015-12-01)

Profiling and targeting cancer stem cell signaling pathways for cancer therapeutics
by: Mia C. Borlongan, et al.
Published: (2023-05-01)

Upregulated expression of Notch1/4 - JAG-1/DLL-1 detected in allergic rhinitis
by: Eric Hjalmarsson, et al.
Published: (2023-05-01)

The use of nonsteroidal anti - inflammatory drugs in polymorbid pathology
by: N S Asfandiyarova, et al.
Published: (2020-01-01)

Targeting the Notch signaling pathway and the Notch ligand, DLL3, in small cell lung cancer
by: Huan Zhang, et al.
Published: (2023-03-01)

Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine
by: Hiromichi Shimizu, et al.
Published: (2014-05-01)

Optogenetic control of NOTCH1 signaling
by: Joanna Kałafut, et al.
Published: (2022-05-01)

Differential Expression of NOTCH-1 and Its Molecular Targets in Response to Metronomic Followed by Conventional Therapy in a Patient with Advanced Triple-Negative Breast Cancer
by: Alice Ilari, et al.
Published: (2024-01-01)

Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer
by: Zhen Zeng, et al.
Published: (2023-10-01)

The potential value of Notch1 and DLL1 in the diagnosis and prognosis of patients with active TB
by: Jinling Xie, et al.
Published: (2023-03-01)

Identification of INFG/STAT1/NOTCH3 as γ-Mangostin's potential targets for overcoming doxorubicin resistance and reducing cancer-associated fibroblasts in triple-negative breast cancer
by: Bashir Lawal, et al.
Published: (2023-07-01)

The Essence of Clinical Practice Guidelines for Lumbar Spinal Stenosis, 2021: 3. Conservative Treatment
by: Katsushi Takeshita
Published: (2023-07-01)

The effects of corticosteroids and nonsteroidal anti-inflammatory drugs, including aspirin, on coagulation
by: Eric Hodgson
Published: (2015-09-01)

Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells
by: Ahmed El-Badawy, et al.
Published: (2018-07-01)

NOTCH1, NOTCH3, NOTCH4, and JAG2 protein levels in human endometrial cancer
by: Aušra Sasnauskienė, et al.
Published: (2014-01-01)

Selective Adsorption of Aqueous Diclofenac Sodium, Naproxen Sodium, and Ibuprofen Using a Stable Fe<sub>3</sub>O<sub>4</sub>–FeBTC Metal–Organic Framework
by: Aldo Arturo Castañeda Ramírez, et al.
Published: (2021-04-01)

Update on immune‐based therapy strategies targeting cancer stem cells
by: Amirhossein Izadpanah, et al.
Published: (2023-09-01)

Evaluating the Magnolol Anticancer Potential in MKN-45 Gastric Cancer Cells
by: Mahsa Naghashpour, et al.
Published: (2023-02-01)

Preliminary Research of Main Components of Dll4/ Notch-VEGF Signaling Pathway Under High-Glucose Stimulation in vitro
by: Gao N, et al.
Published: (2022-04-01)

The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness
by: Fengtian Li, et al.
Published: (2020-06-01)

Targeting deubiquitinating enzymes in cancer stem cells
by: Hu Lei, et al.
Published: (2017-11-01)

RGD-Coated Polymer Nanoworms for Enriching Cancer Stem Cells
by: Yushu Gu, et al.
Published: (2022-12-01)

Regulation of Notch1 Signalling by Long Non-Coding RNAs in Cancers and Other Health Disorders
by: Joanna Kałafut, et al.
Published: (2023-08-01)

Public Knowledge, Attitudes, and Practices Regarding the Use of Over-The-Counter (OTC) Analgesics in Indonesia: A Cross-Sectional Study
by: Sinuraya RK, et al.
Published: (2023-10-01)

Nonsteroidal anti-inflammatory drugs in therapeutic practice: nimesulide in focus
by: G. G. Ketova, et al.
Published: (2018-11-01)

BIOPHARMACEUTICAL PROPERTIES OF THE NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
by: Y. I. Kulinich
Published: (2022-12-01)

Review of the safety of nonsteroidal anti-inflammatory drugs and selective cyclo-oxygenase-2 inhibitors
by: G. S. Tarr, et al.
Published: (2015-05-01)

Prostaglandins and the relation with Inflammation Pain
by: Hilda Leonor González Olaya
Published: (1998-08-01)

Endothelial Jagged1 Antagonizes Dll4/Notch Signaling in Decidual Angiogenesis during Early Mouse Pregnancy
by: Nicole M. Marchetto, et al.
Published: (2020-09-01)

Cancer stem cell biomarkers: critical roles, challenges, clinical applications and perspectives in cancer therapy
by: Elham Bahrami Salehloo, et al.
Published: (2022-05-01)

DLL3 regulates Notch signaling in small cell lung cancer
by: Jun W. Kim, et al.
Published: (2022-12-01)

Cancer Stem Cells and Targeting Strategies
by: Luisa Barbato, et al.
Published: (2019-08-01)

Recurrent episodes of isolated periorbital angioedema associated with separate courses of ibuprofen: A diagnostic dilemma
by: Kunal Sareen, et al.
Published: (2022-01-01)