COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy)
Background: Measles, mumps, and rubella (MMR) vaccines have been suggested as preventive measures to protect subjects from the worst sequelae of COVID-19 infection because neutralizing antibodies can cross-react with other viruses. Aim: To verify COVID-19 infection in MMR vaccinated and non-vaccinat...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-04-01
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| Series: | Vaccine: X |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590136222000079 |
| _version_ | 1819026049930887168 |
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| author | Eleonora Cattaruzza Lucia Radillo Federico Ronchese Corrado Negro Francesca Rui Paola De Michieli Francesca Larese Filon |
| author_facet | Eleonora Cattaruzza Lucia Radillo Federico Ronchese Corrado Negro Francesca Rui Paola De Michieli Francesca Larese Filon |
| author_sort | Eleonora Cattaruzza |
| collection | DOAJ |
| description | Background: Measles, mumps, and rubella (MMR) vaccines have been suggested as preventive measures to protect subjects from the worst sequelae of COVID-19 infection because neutralizing antibodies can cross-react with other viruses. Aim: To verify COVID-19 infection in MMR vaccinated and non-vaccinated healthcare workers and medical students in Trieste Hospitals. Results: Nurse aids resulted in significantly more infections than structured physicians (OR 1.80; 95% CI 1.14–2.80) while students resulted in less infections (OR, 0.66; 95% CI 0.43–1.01). The presence of an MMR vaccination was inversely associated with COVID-19 (OR, 0.77; 95% CI 0.61–0.96) but only in univariate analysis. In the multivariable logistic regression analysis, MMR vaccination lost statistical significance (OR, 0.86; 95%CI 0.62–1.20).On 13 HCWs hospitalized for COVID-19, 11 resulted not vaccinated for MMR. Discussion: Our study found a mild, non-significant reduction in SARS-CoV-2 infections in workers vaccinated with MMR. |
| first_indexed | 2024-12-21T05:20:24Z |
| format | Article |
| id | doaj.art-783dcd5ab0d24b53bf995e675486043d |
| institution | Directory Open Access Journal |
| issn | 2590-1362 |
| language | English |
| last_indexed | 2024-12-21T05:20:24Z |
| publishDate | 2022-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Vaccine: X |
| spelling | doaj.art-783dcd5ab0d24b53bf995e675486043d2022-12-21T19:14:49ZengElsevierVaccine: X2590-13622022-04-0110100147COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy)Eleonora Cattaruzza0Lucia Radillo1Federico Ronchese2Corrado Negro3Francesca Rui4Paola De Michieli5Francesca Larese Filon6Scuola di Specializzazione in Medicina del Lavoro, Università di Trieste; Unità Clinica di Medicina del Lavoro, Università di Trieste, Azienda Sanitaria Universitaria Integrata di Trieste, ItalyScuola di Specializzazione in Medicina del Lavoro, Università di Trieste; Unità Clinica di Medicina del Lavoro, Università di Trieste, Azienda Sanitaria Universitaria Integrata di Trieste, ItalyScuola di Specializzazione in Medicina del Lavoro, Università di Trieste; Unità Clinica di Medicina del Lavoro, Università di Trieste, Azienda Sanitaria Universitaria Integrata di Trieste, ItalyScuola di Specializzazione in Medicina del Lavoro, Università di Trieste; Unità Clinica di Medicina del Lavoro, Università di Trieste, Azienda Sanitaria Universitaria Integrata di Trieste, ItalyScuola di Specializzazione in Medicina del Lavoro, Università di Trieste; Unità Clinica di Medicina del Lavoro, Università di Trieste, Azienda Sanitaria Universitaria Integrata di Trieste, ItalyScuola di Specializzazione in Medicina del Lavoro, Università di Trieste; Unità Clinica di Medicina del Lavoro, Università di Trieste, Azienda Sanitaria Universitaria Integrata di Trieste, ItalyCorresponding author.; Scuola di Specializzazione in Medicina del Lavoro, Università di Trieste; Unità Clinica di Medicina del Lavoro, Università di Trieste, Azienda Sanitaria Universitaria Integrata di Trieste, ItalyBackground: Measles, mumps, and rubella (MMR) vaccines have been suggested as preventive measures to protect subjects from the worst sequelae of COVID-19 infection because neutralizing antibodies can cross-react with other viruses. Aim: To verify COVID-19 infection in MMR vaccinated and non-vaccinated healthcare workers and medical students in Trieste Hospitals. Results: Nurse aids resulted in significantly more infections than structured physicians (OR 1.80; 95% CI 1.14–2.80) while students resulted in less infections (OR, 0.66; 95% CI 0.43–1.01). The presence of an MMR vaccination was inversely associated with COVID-19 (OR, 0.77; 95% CI 0.61–0.96) but only in univariate analysis. In the multivariable logistic regression analysis, MMR vaccination lost statistical significance (OR, 0.86; 95%CI 0.62–1.20).On 13 HCWs hospitalized for COVID-19, 11 resulted not vaccinated for MMR. Discussion: Our study found a mild, non-significant reduction in SARS-CoV-2 infections in workers vaccinated with MMR.http://www.sciencedirect.com/science/article/pii/S2590136222000079 |
| spellingShingle | Eleonora Cattaruzza Lucia Radillo Federico Ronchese Corrado Negro Francesca Rui Paola De Michieli Francesca Larese Filon COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy) Vaccine: X |
| title | COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy) |
| title_full | COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy) |
| title_fullStr | COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy) |
| title_full_unstemmed | COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy) |
| title_short | COVID-19 susceptibility and vaccination coverage for measles, rubella and mumps in students and healthcare workers in Trieste hospitals (NE Italy) |
| title_sort | covid 19 susceptibility and vaccination coverage for measles rubella and mumps in students and healthcare workers in trieste hospitals ne italy |
| url | http://www.sciencedirect.com/science/article/pii/S2590136222000079 |
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