Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis

Today, acute rhinosinusitis is one of the most common infectious diseases in the world. Usually, acute rhinosinusitis develops against the background of acute respiratory viral infection caused by influenza viruses, parainfluenza, respiratory syncytial virus, adenoviruses, or rhinoviruses. At the sa...

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Main Authors: S. V. Ryazantsev, A. A. Krivopalov, P. A. Shamkina, K. A. Lezhneva, O. S. Donskaya
Format: Article
Language:Russian
Published: Remedium Group LLC 2020-11-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/5840
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author S. V. Ryazantsev
A. A. Krivopalov
P. A. Shamkina
K. A. Lezhneva
O. S. Donskaya
author_facet S. V. Ryazantsev
A. A. Krivopalov
P. A. Shamkina
K. A. Lezhneva
O. S. Donskaya
author_sort S. V. Ryazantsev
collection DOAJ
description Today, acute rhinosinusitis is one of the most common infectious diseases in the world. Usually, acute rhinosinusitis develops against the background of acute respiratory viral infection caused by influenza viruses, parainfluenza, respiratory syncytial virus, adenoviruses, or rhinoviruses. At the same time, in 1–2% of cases, the course of acute respiratory viral infection is complicated by bacterial sinusitis. At the same time, in 1–2% of cases, the course of acute respiratory viral infection is complicated by bacterial sinusitis. Considering the stages of the process, it is extremely important to adequately prescribe therapy at the onset of acute respiratory viral infection before the development of symptoms of acute rhinosinusitis, since the prognosis largely depends on its effectiveness. Treatment of acute rhinosinusitis is aimed at relieving the symptoms of the disease, improving aeration of the nasal cavity and paranasal sinuses, restoring the functions of mucociliary transport, and in the case of bacterial agent attachment, at the eradication of the pathogen. Such problems are solved through complex therapy, including irrigation measures, decongestants, topical glucocorticosteroids, and antibiotics if indicated. To improve the function of mucociliary transport the standard therapy of acute rhinosinusitis is combined with herbal medicines, which have a mucoactive, secretomotor, secretolytic and anti-inflammatory effects. The article presents data on the pharmacokinetics and pharmacodynamics of the drug Sinupret, the results of experimental studies and clinical studies that prove the high effectiveness and safety of the drug in the complex treatment of acute rhinosinusitis. One of the important advantages of using the herbal drug Sinupret is an increase the effectiveness of antibiotic therapy, which allows for a faster recovery in bacterial sinusitis, and moreover in cases of acute post-viral sinusitis, Sinupret can be used as monotherapy.
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spelling doaj.art-783e26d2785243f19d4698f28230e37d2023-04-23T06:56:57ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902020-11-01016182510.21518/2079-701X-2020-16-18-255308Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitisS. V. Ryazantsev0A. A. Krivopalov1P. A. Shamkina2K. A. Lezhneva3O. S. Donskaya4St Petersburg Research Institute of Ear, Throat, Nose and SpeechSt Petersburg Research Institute of Ear, Throat, Nose and SpeechSt Petersburg Research Institute of Ear, Throat, Nose and SpeechSt Petersburg Research Institute of Ear, Throat, Nose and SpeechFederal State Budgetary Educational Institution of Higher Education “Pavlov First Saint Petersburg State Medical University” of the Ministry of Healthcare of Russian FederationToday, acute rhinosinusitis is one of the most common infectious diseases in the world. Usually, acute rhinosinusitis develops against the background of acute respiratory viral infection caused by influenza viruses, parainfluenza, respiratory syncytial virus, adenoviruses, or rhinoviruses. At the same time, in 1–2% of cases, the course of acute respiratory viral infection is complicated by bacterial sinusitis. At the same time, in 1–2% of cases, the course of acute respiratory viral infection is complicated by bacterial sinusitis. Considering the stages of the process, it is extremely important to adequately prescribe therapy at the onset of acute respiratory viral infection before the development of symptoms of acute rhinosinusitis, since the prognosis largely depends on its effectiveness. Treatment of acute rhinosinusitis is aimed at relieving the symptoms of the disease, improving aeration of the nasal cavity and paranasal sinuses, restoring the functions of mucociliary transport, and in the case of bacterial agent attachment, at the eradication of the pathogen. Such problems are solved through complex therapy, including irrigation measures, decongestants, topical glucocorticosteroids, and antibiotics if indicated. To improve the function of mucociliary transport the standard therapy of acute rhinosinusitis is combined with herbal medicines, which have a mucoactive, secretomotor, secretolytic and anti-inflammatory effects. The article presents data on the pharmacokinetics and pharmacodynamics of the drug Sinupret, the results of experimental studies and clinical studies that prove the high effectiveness and safety of the drug in the complex treatment of acute rhinosinusitis. One of the important advantages of using the herbal drug Sinupret is an increase the effectiveness of antibiotic therapy, which allows for a faster recovery in bacterial sinusitis, and moreover in cases of acute post-viral sinusitis, Sinupret can be used as monotherapy.https://www.med-sovet.pro/jour/article/view/5840acute sinusitisacute bacterial rhinosinusitiscomplex therapysecretolytic therapyherbal drugs
spellingShingle S. V. Ryazantsev
A. A. Krivopalov
P. A. Shamkina
K. A. Lezhneva
O. S. Donskaya
Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis
Медицинский совет
acute sinusitis
acute bacterial rhinosinusitis
complex therapy
secretolytic therapy
herbal drugs
title Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis
title_full Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis
title_fullStr Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis
title_full_unstemmed Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis
title_short Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis
title_sort highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis
topic acute sinusitis
acute bacterial rhinosinusitis
complex therapy
secretolytic therapy
herbal drugs
url https://www.med-sovet.pro/jour/article/view/5840
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AT aakrivopalov highlightsofprescribingherbalmedicinesinthecomplextherapyofacuterhinosinusitis
AT pashamkina highlightsofprescribingherbalmedicinesinthecomplextherapyofacuterhinosinusitis
AT kalezhneva highlightsofprescribingherbalmedicinesinthecomplextherapyofacuterhinosinusitis
AT osdonskaya highlightsofprescribingherbalmedicinesinthecomplextherapyofacuterhinosinusitis