Pediatric spitzoid lesions of the ear: a single center experience and review of literature
Background and objectives. Spitzoid lesions are challenging melanocytic lesions comprising benign, intermediate, and malignant lesions. In this study, we aimed to analyze the diagnostic accuracy of clinical and dermatoscopical evaluation of pediatric spitzoid ear lesions. Materials and Methods. We...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2023-06-01
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| Series: | Dermatology Reports |
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| Online Access: | https://www.pagepress.org/journals/index.php/dr/article/view/9642 |
| _version_ | 1797809983362957312 |
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| author | Gianmaria Viglizzo Astrid Herzum Lodovica Gariazzo Ehab Garibeh Corrado Occella |
| author_facet | Gianmaria Viglizzo Astrid Herzum Lodovica Gariazzo Ehab Garibeh Corrado Occella |
| author_sort | Gianmaria Viglizzo |
| collection | DOAJ |
| description |
Background and objectives. Spitzoid lesions are challenging melanocytic lesions comprising benign, intermediate, and malignant lesions. In this study, we aimed to analyze the diagnostic accuracy of clinical and dermatoscopical evaluation of pediatric spitzoid ear lesions. Materials and Methods. We collected and analyzed, clinically, dermatoscopically and histologically, pediatric spitzoid ear lesions. Also, we conducted a systematic review of literature. Results. At the Pediatric Hospital Gaslini, excision and histopathological evaluation were performed on eight cases: 87.5% of lesions were consistent with Spitz nevus (SN), and 12.5% with atypical Spitz tumor AST. Notably, multiple (≥2) dermatoscopical irregularities were present in five of seven SN (71%), yet none were found in AST 0/1 (0%). (Fisher’s exact test p=0.375). From systematic research of the literature, 9 patients were included in this review. At histology, 88.9% were SN, and 11% AST. Of note, also in literature, multiple dermatoscopical irregularities, were present in most SN (75%, 6/8), not in the identified AST (0%, 0/1) (p=0.3333). Conclusions. We present a monocentric study on pediatric spitzoid ear lesions. Importantly, dermatoscopical irregularities were not significantly associated to AST, neither in our series, nor in the reviewed literature (respectively p=0.375 and p=0.3333) supporting the fact that relying only on the dermatoscopical aspect of spitzoid lesions is not accurate enough for the special site of the ear, where dermatoscopy could be actually misleading.
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| first_indexed | 2024-03-13T07:02:16Z |
| format | Article |
| id | doaj.art-78453929ad1e4d4284d8abc820ac0333 |
| institution | Directory Open Access Journal |
| issn | 2036-7392 2036-7406 |
| language | English |
| last_indexed | 2024-03-13T07:02:16Z |
| publishDate | 2023-06-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj.art-78453929ad1e4d4284d8abc820ac03332023-06-06T18:02:34ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062023-06-0110.4081/dr.2023.9642Pediatric spitzoid lesions of the ear: a single center experience and review of literatureGianmaria Viglizzo0Astrid Herzum1Lodovica Gariazzo2Ehab Garibeh3Corrado Occella4Dermatology Unit, IRCCS Istituto Giannina Gaslini, GenovaDermatology Unit, IRCCS Istituto Giannina Gaslini, GenovaDermatology Unit, IRCCS Istituto Giannina Gaslini, GenovaDermatology Unit, IRCCS Istituto Giannina Gaslini, GenovaDermatology Unit, IRCCS Istituto Giannina Gaslini, Genova Background and objectives. Spitzoid lesions are challenging melanocytic lesions comprising benign, intermediate, and malignant lesions. In this study, we aimed to analyze the diagnostic accuracy of clinical and dermatoscopical evaluation of pediatric spitzoid ear lesions. Materials and Methods. We collected and analyzed, clinically, dermatoscopically and histologically, pediatric spitzoid ear lesions. Also, we conducted a systematic review of literature. Results. At the Pediatric Hospital Gaslini, excision and histopathological evaluation were performed on eight cases: 87.5% of lesions were consistent with Spitz nevus (SN), and 12.5% with atypical Spitz tumor AST. Notably, multiple (≥2) dermatoscopical irregularities were present in five of seven SN (71%), yet none were found in AST 0/1 (0%). (Fisher’s exact test p=0.375). From systematic research of the literature, 9 patients were included in this review. At histology, 88.9% were SN, and 11% AST. Of note, also in literature, multiple dermatoscopical irregularities, were present in most SN (75%, 6/8), not in the identified AST (0%, 0/1) (p=0.3333). Conclusions. We present a monocentric study on pediatric spitzoid ear lesions. Importantly, dermatoscopical irregularities were not significantly associated to AST, neither in our series, nor in the reviewed literature (respectively p=0.375 and p=0.3333) supporting the fact that relying only on the dermatoscopical aspect of spitzoid lesions is not accurate enough for the special site of the ear, where dermatoscopy could be actually misleading. https://www.pagepress.org/journals/index.php/dr/article/view/9642Spitz nevuspediatric spitzear lesionear spitz |
| spellingShingle | Gianmaria Viglizzo Astrid Herzum Lodovica Gariazzo Ehab Garibeh Corrado Occella Pediatric spitzoid lesions of the ear: a single center experience and review of literature Dermatology Reports Spitz nevus pediatric spitz ear lesion ear spitz |
| title | Pediatric spitzoid lesions of the ear: a single center experience and review of literature |
| title_full | Pediatric spitzoid lesions of the ear: a single center experience and review of literature |
| title_fullStr | Pediatric spitzoid lesions of the ear: a single center experience and review of literature |
| title_full_unstemmed | Pediatric spitzoid lesions of the ear: a single center experience and review of literature |
| title_short | Pediatric spitzoid lesions of the ear: a single center experience and review of literature |
| title_sort | pediatric spitzoid lesions of the ear a single center experience and review of literature |
| topic | Spitz nevus pediatric spitz ear lesion ear spitz |
| url | https://www.pagepress.org/journals/index.php/dr/article/view/9642 |
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