QBD approach for the development of hesperetin loaded colloidal nanosponges for sustained delivery: In-vitro, ex-vivo, and in-vivo assessment

QBD approach for the development of hesperetin loaded colloidal nanosponges for sustained delivery: In-vitro, ex-vivo, and in-vivo assessment

Hesperetin (HT) is a polyphenolic compound with anti-carcinogenic, tumor necrosis, and anti-oxidant properties. The present study reports the fabrication, optimization, and evaluation of HT-loaded nanosponges (HTN)- based gel (HTNG) for sustained anti-inflammatory effect. HTN formulation was prepare...

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Bibliographic Details
Main Authors: Kitty Rodrigues, Sameer Nadaf, Nilesh Rarokar, Nilambari Gurav, Pradnya Jagtap, Prashant Mali, Muniappan Ayyanar, Mohan Kalaskar, Shailendra Gurav
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:OpenNano
Subjects:
Bioavailability
Bioflavonoid
Colloidal carriers
Hesperetin
Nanosponges
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952022000081

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