Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage

Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage

The functional activities of Anguimorpha lizard venoms have received less attention compared to serpent lineages. Bite victims of varanid lizards often report persistent bleeding exceeding that expected for the mechanical damage of the bite. Research to date has identified the blockage of platelet a...

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Bibliographic Details
Main Authors: James S. Dobson, Christina N. Zdenek, Chris Hay, Aude Violette, Rudy Fourmy, Chip Cochran, Bryan G. Fry
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Toxins
Subjects:
Anguimorpha
<i>Varanus</i>
<i>Heloderma</i>
lizard venom
fibrinogenolytic
anticoagulation
Online Access:https://www.mdpi.com/2072-6651/11/5/255

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