Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use
Background: Psoriasis is a chronic inflammatory disease that has a negative impact on patients' quality of life. Patients with mild–moderate psoriasis can be treated with topical medications, such as the combination drug calcipotriol/betamethasone dipropionate (Cal/BD). Objectives: This st...
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| Format: | Article |
| Language: | English |
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Mattioli1885
2021-05-01
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| Series: | Dermatology Practical & Conceptual |
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| Online Access: | http://dpcj.org/index.php/dpc/article/view/1595 |
| _version_ | 1818892554678042624 |
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| author | Francisco J. Navarro-Triviño Mario Lozano-Lozano Ricardo Ruiz-Villaverde |
| author_facet | Francisco J. Navarro-Triviño Mario Lozano-Lozano Ricardo Ruiz-Villaverde |
| author_sort | Francisco J. Navarro-Triviño |
| collection | DOAJ |
| description | Background: Psoriasis is a chronic inflammatory disease that has a negative impact on patients' quality of life. Patients with mild–moderate psoriasis can be treated with topical medications, such as the combination drug calcipotriol/betamethasone dipropionate (Cal/BD).
Objectives: This study investigated the adherence of psoriasis patients to therapy with Cal/BD aerosol foam, as well as their satisfaction with the treatment’s efficacy, safety, and effect on their quality of life.
Methods: Patients with mild–moderate plaque psoriasis were eligible to participate in this open-label, non-placebo controlled, prospective single-center study. Adherence to treatment was assessed using the Morisky-Green scale 4 and 12 weeks after the start of treatment. Satisfaction with the treatment was assessed using the abbreviated Treatment Satisfaction Questionnaire for Medication (TSQM-9). The severity of psoriasis was assessed on the mIGA and PGA scales, and the impact on quality of life was assessed using the PDI and DLQI scales.
Results: A total of 65 patients entered the study. Adherence to treatment was good, with 73.8% of patients showing high adherence at 12 weeks. Satisfaction was also good, with 46 patients (70.8%) being completely satisfied.
Conclusions: Over a 4-week period, patients treated with Cal/BD aerosol foam had significant improvement in disease severity that was directly related to treatment adherence. |
| first_indexed | 2024-12-19T17:58:33Z |
| format | Article |
| id | doaj.art-784adb0dd8e64114a30eb4830d985e78 |
| institution | Directory Open Access Journal |
| issn | 2160-9381 |
| language | English |
| last_indexed | 2024-12-19T17:58:33Z |
| publishDate | 2021-05-01 |
| publisher | Mattioli1885 |
| record_format | Article |
| series | Dermatology Practical & Conceptual |
| spelling | doaj.art-784adb0dd8e64114a30eb4830d985e782022-12-21T20:11:45ZengMattioli1885Dermatology Practical & Conceptual2160-93812021-05-0110.5826/dpc.1103a56Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily UseFrancisco J. Navarro-Triviño0Mario Lozano-Lozano1Ricardo Ruiz-Villaverde2Department of Contact Eczema and Immunoallergic Diseases, Hospital Universitario San Cecilio, Granada, SpainDepartment of Physical Therapy, Faculty of Health Sciences, and University of Granada & Sport and Health Joint University Institute (iMUDS), Granada, SpainDepartment of Psoriasis, Dermatology, Hospital Universitario San Cecilio, Granada, SpainBackground: Psoriasis is a chronic inflammatory disease that has a negative impact on patients' quality of life. Patients with mild–moderate psoriasis can be treated with topical medications, such as the combination drug calcipotriol/betamethasone dipropionate (Cal/BD). Objectives: This study investigated the adherence of psoriasis patients to therapy with Cal/BD aerosol foam, as well as their satisfaction with the treatment’s efficacy, safety, and effect on their quality of life. Methods: Patients with mild–moderate plaque psoriasis were eligible to participate in this open-label, non-placebo controlled, prospective single-center study. Adherence to treatment was assessed using the Morisky-Green scale 4 and 12 weeks after the start of treatment. Satisfaction with the treatment was assessed using the abbreviated Treatment Satisfaction Questionnaire for Medication (TSQM-9). The severity of psoriasis was assessed on the mIGA and PGA scales, and the impact on quality of life was assessed using the PDI and DLQI scales. Results: A total of 65 patients entered the study. Adherence to treatment was good, with 73.8% of patients showing high adherence at 12 weeks. Satisfaction was also good, with 46 patients (70.8%) being completely satisfied. Conclusions: Over a 4-week period, patients treated with Cal/BD aerosol foam had significant improvement in disease severity that was directly related to treatment adherence.http://dpcj.org/index.php/dpc/article/view/1595adherencesatisfactioncalcipotriol/bethamethasoneaersolo foampsoriasis |
| spellingShingle | Francisco J. Navarro-Triviño Mario Lozano-Lozano Ricardo Ruiz-Villaverde Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use Dermatology Practical & Conceptual adherence satisfaction calcipotriol/bethamethasone aersolo foam psoriasis |
| title | Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use |
| title_full | Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use |
| title_fullStr | Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use |
| title_full_unstemmed | Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use |
| title_short | Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use |
| title_sort | calcipotriol betamethasone dipropionate aerosol foam for plaque psoriasis a prospective observational non interventional single center study of patient adherence and satisfaction in daily use |
| topic | adherence satisfaction calcipotriol/bethamethasone aersolo foam psoriasis |
| url | http://dpcj.org/index.php/dpc/article/view/1595 |
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