Lower peripheral blood Toll-like receptor 3 expression is associated with an unfavorable outcome in severe COVID-19 patients

Lower peripheral blood Toll-like receptor 3 expression is associated with an unfavorable outcome in severe COVID-19 patients

Abstract The role of innate immunity in COVID-19 is not completely understood. Therefore, this study explored the impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection on the expression of Pattern Recognition Receptors (PRRs) in peripheral blood cells and their correlated...

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Main Authors: Maria Clara Saad Menezes, Alicia Dudy Müller Veiga, Thais Martins de Lima, Suely Kunimi Kubo Ariga, Hermes Vieira Barbeiro, Claudia de Lucena Moreira, Agnes Araujo Sardinha Pinto, Rodrigo Antonio Brandao, Julio Flavio Marchini, Julio Cesar Alencar, Lucas Oliveira Marino, Luz Marina Gomez, Niels Olsen Saraiva Camara, Heraldo P. Souza
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94624-4

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