Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets.

Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets.

The transbilayer movement of phosphatidylserine mediates the platelet procoagulant activity during collagen stimulation. The Rho-associated coiled-coil kinase (ROCK) inhibitor Y-27632 inhibits senescence induced but not activation induced phosphatidylserine exposure. To investigate further the speci...

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Bibliographic Details
Main Authors: Swapan K Dasgupta, Anhquyen Le, Sandra B Haudek, Mark L Entman, Rolando E Rumbaut, Perumal Thiagarajan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3865301?pdf=render

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