Diversity of Bacterial Biosynthetic Genes in Maritime Antarctica

Diversity of Bacterial Biosynthetic Genes in Maritime Antarctica

Bacterial natural products (NPs) are still a major source of new drug leads. Polyketides (PKs) and non-ribosomal peptides (NRP) are two pharmaceutically important families of NPs and recent studies have revealed Antarctica to harbor endemic polyketide synthase (PKS) and non-ribosomal peptide synthet...

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Bibliographic Details
Main Authors: Adriana Rego, António G. G. Sousa, João P. Santos, Francisco Pascoal, João Canário, Pedro N. Leão, Catarina Magalhães
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Microorganisms
Subjects:
antarctica
polyketides (pks)
non-ribosomal peptides (nrps)
biosynthetic genes
computational bioprospection
ketosynthase (ks)
adenylation (ad)
natural products (nps)
Online Access:https://www.mdpi.com/2076-2607/8/2/279

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