Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains

Ion conductivity and the gating characteristics of tetrameric glutamate receptor ion channels are determined by their subunit composition. Competitive homo- and hetero-dimerization of their amino-terminal domains (ATDs) is a key step controlling assembly. Here we measured systematically the thermody...

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Bibliographic Details
Main Authors: Huaying Zhao, Suvendu Lomash, Sagar Chittori, Carla Glasser, Mark L Mayer, Peter Schuck
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
glutamate receptors
protein interactions
sedimentation velocity
Online Access:https://elifesciences.org/articles/32056

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