Design, Synthesis, and Anti-Hepatocellular Carcinoma Evaluation of Sesquiterpene Lactone Epimers Trilobolide-6-<i>O</i>-isobutyrate Analogs

Design, Synthesis, and Anti-Hepatocellular Carcinoma Evaluation of Sesquiterpene Lactone Epimers Trilobolide-6-<i>O</i>-isobutyrate Analogs

Hepatocellular carcinoma (HCC), one of the most common malignant cancers with a low 5-year survival rate, is the third leading cause of cancer-related deaths worldwide. The finding of novel agents and strategies for the treatment of HCC is an urgent need. Sesquiterpene lactones (SLs) have attracted...

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Bibliographic Details
Main Authors: Xiuqiao Zhou, Guohui Yi, Yiming Qian, Xiaorong Yang, Guangying Chen, Yang Hui, Wenhao Chen
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
sesquiterpene lactones
synthesis
anti-hepatocellular carcinoma evaluation
Online Access:https://www.mdpi.com/1420-3049/29/2/393

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