Overexpression of HSP70 attenuates sarcopenia by suppressing the expression of miR‐133b

Overexpression of HSP70 attenuates sarcopenia by suppressing the expression of miR‐133b

Abstract Background The aim of the present investigation is to evaluate the effect of the overexpression of inducible 70‐kDa heat shock protein (HSP70) on sarcopenic muscles of aged mice. Methods Tibialis anterior muscles of aged and young transgenic mice overexpressing HSP70 and wild‐type mice were...

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Bibliographic Details
Main Authors: Tábata L. Nascimento, Ruben Mestril, Elen H. Miyabara
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:JCSM Rapid Communications
Subjects:
Muscle wasting
Sarcopenia
Heat shock protein 70
miR‐133b
Online Access:https://doi.org/10.1002/rco2.12

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