RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking.

RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking.

Receptor internalization from the cell surface occurs through several mechanisms. Some of these mechanisms, such as clathrin coated pits, are well understood. The M(2) muscarinic acetylcholine receptor undergoes internalization via a poorly-defined clathrin-independent mechanism. We used isotope cod...

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Bibliographic Details
Main Authors: Cindy L Reiner, Jennifer S McCullar, Rebecca L Kow, Joshua H Le, David R Goodlett, Neil M Nathanson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2958127?pdf=render

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