Dried Blood Spot in Laboratory: Directions and Prospects
Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or geno...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/10/4/248 |
| _version_ | 1797569783585046528 |
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| author | Kristina Malsagova Artur Kopylov Alexander Stepanov Tatyana Butkova Alexander Izotov Anna Kaysheva |
| author_facet | Kristina Malsagova Artur Kopylov Alexander Stepanov Tatyana Butkova Alexander Izotov Anna Kaysheva |
| author_sort | Kristina Malsagova |
| collection | DOAJ |
| description | Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or genomic methods can be employed for analysis after drying the sample. DBS has been described as the most appropriate method for biomaterial sampling due to specific associated inherent advantages, including the small volumes of biomaterials required, the absence of a need for special conditions for samples’ storage and transportation, improved stability of analytes and reduced risk of infection resulting from contaminated samples. This review illustrates information on the current state of DBS technology, which can be useful and helpful for biomedical researchers. The prospects of using this technology to assess the metabolomic profile, assessment, diagnosis of communicable diseases are demonstrated. |
| first_indexed | 2024-03-10T20:16:27Z |
| format | Article |
| id | doaj.art-7858d69afaa94abdaf3ccdfa1f7b43be |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T20:16:27Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-7858d69afaa94abdaf3ccdfa1f7b43be2023-11-19T22:31:23ZengMDPI AGDiagnostics2075-44182020-04-0110424810.3390/diagnostics10040248Dried Blood Spot in Laboratory: Directions and ProspectsKristina Malsagova0Artur Kopylov1Alexander Stepanov2Tatyana Butkova3Alexander Izotov4Anna Kaysheva5Institute of Biomedical Chemistry, Biobanking Group, Moscow 109028, RussiaInstitute of Biomedical Chemistry, Biobanking Group, Moscow 109028, RussiaInstitute of Biomedical Chemistry, Biobanking Group, Moscow 109028, RussiaInstitute of Biomedical Chemistry, Biobanking Group, Moscow 109028, RussiaInstitute of Biomedical Chemistry, Biobanking Group, Moscow 109028, RussiaInstitute of Biomedical Chemistry, Biobanking Group, Moscow 109028, RussiaOver the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or genomic methods can be employed for analysis after drying the sample. DBS has been described as the most appropriate method for biomaterial sampling due to specific associated inherent advantages, including the small volumes of biomaterials required, the absence of a need for special conditions for samples’ storage and transportation, improved stability of analytes and reduced risk of infection resulting from contaminated samples. This review illustrates information on the current state of DBS technology, which can be useful and helpful for biomedical researchers. The prospects of using this technology to assess the metabolomic profile, assessment, diagnosis of communicable diseases are demonstrated.https://www.mdpi.com/2075-4418/10/4/248dried blood spots (DBS)serodiagnosisELISAMSpostgenomic technologies |
| spellingShingle | Kristina Malsagova Artur Kopylov Alexander Stepanov Tatyana Butkova Alexander Izotov Anna Kaysheva Dried Blood Spot in Laboratory: Directions and Prospects Diagnostics dried blood spots (DBS) serodiagnosis ELISA MS postgenomic technologies |
| title | Dried Blood Spot in Laboratory: Directions and Prospects |
| title_full | Dried Blood Spot in Laboratory: Directions and Prospects |
| title_fullStr | Dried Blood Spot in Laboratory: Directions and Prospects |
| title_full_unstemmed | Dried Blood Spot in Laboratory: Directions and Prospects |
| title_short | Dried Blood Spot in Laboratory: Directions and Prospects |
| title_sort | dried blood spot in laboratory directions and prospects |
| topic | dried blood spots (DBS) serodiagnosis ELISA MS postgenomic technologies |
| url | https://www.mdpi.com/2075-4418/10/4/248 |
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