Japanese encephalitis: a review of the Indian perspective

Japanese encephalitis virus (JEV) causes Japanese encephalitis, which is a leading form of viral encephalitis in Asia, with around 50,000 cases and 10,000 deaths per year in children below 15 years of age. The JEV has shown a tendency to extend to other geographic regions. Case fatality averages 30%...

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Main Authors: Sarika Tiwari, Rishi Kumar Singh, Ruchi Tiwari, Tapan N. Dhole
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600011&lng=en&tlng=en
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author Sarika Tiwari
Rishi Kumar Singh
Ruchi Tiwari
Tapan N. Dhole
author_facet Sarika Tiwari
Rishi Kumar Singh
Ruchi Tiwari
Tapan N. Dhole
author_sort Sarika Tiwari
collection DOAJ
description Japanese encephalitis virus (JEV) causes Japanese encephalitis, which is a leading form of viral encephalitis in Asia, with around 50,000 cases and 10,000 deaths per year in children below 15 years of age. The JEV has shown a tendency to extend to other geographic regions. Case fatality averages 30% and a high percentage of the survivors are left with permanent neuropsychiatric sequelae. Currently, there is no cure for JEV, and treatment is mainly supportive. Patients are not infectious, but should avoid further mosquito bites. A number of antiviral agents have been investigated; however, none of these have convincingly been shown to improve the outcome of JEV. In this review, the current knowledge of the epidemiology and the pathogenesis of this deadly disease have been summarized.
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spelling doaj.art-7858da6964f14b0882e17992d786e1f52022-12-22T01:17:35ZengElsevierBrazilian Journal of Infectious Diseases1678-439116656457310.1016/j.bjid.2012.10.004S1413-86702012000600011Japanese encephalitis: a review of the Indian perspectiveSarika Tiwari0Rishi Kumar Singh1Ruchi Tiwari2Tapan N. Dhole3Sanjay Gandhi Post Graduate Institute of Medical SciencesSanjay Gandhi Post Graduate Institute of Medical SciencesSanjay Gandhi Post Graduate Institute of Medical SciencesSanjay Gandhi Post Graduate Institute of Medical SciencesJapanese encephalitis virus (JEV) causes Japanese encephalitis, which is a leading form of viral encephalitis in Asia, with around 50,000 cases and 10,000 deaths per year in children below 15 years of age. The JEV has shown a tendency to extend to other geographic regions. Case fatality averages 30% and a high percentage of the survivors are left with permanent neuropsychiatric sequelae. Currently, there is no cure for JEV, and treatment is mainly supportive. Patients are not infectious, but should avoid further mosquito bites. A number of antiviral agents have been investigated; however, none of these have convincingly been shown to improve the outcome of JEV. In this review, the current knowledge of the epidemiology and the pathogenesis of this deadly disease have been summarized.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600011&lng=en&tlng=enEpidemiologyPathogenesisVector born diseasesEpidemics
spellingShingle Sarika Tiwari
Rishi Kumar Singh
Ruchi Tiwari
Tapan N. Dhole
Japanese encephalitis: a review of the Indian perspective
Brazilian Journal of Infectious Diseases
Epidemiology
Pathogenesis
Vector born diseases
Epidemics
title Japanese encephalitis: a review of the Indian perspective
title_full Japanese encephalitis: a review of the Indian perspective
title_fullStr Japanese encephalitis: a review of the Indian perspective
title_full_unstemmed Japanese encephalitis: a review of the Indian perspective
title_short Japanese encephalitis: a review of the Indian perspective
title_sort japanese encephalitis a review of the indian perspective
topic Epidemiology
Pathogenesis
Vector born diseases
Epidemics
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600011&lng=en&tlng=en
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