Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature

Teratoma is a type of germ cell tumor layer that appears in the gonadal, sacrococcygeal, mediastinal, and retroperitoneal regions. Primary retroperitoneal teratoma is rare and asymptomatic but can present with symptoms due to a mass effect on neighboring organs. These tumors have to be considered in...

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Main Authors: Negar Safaei, Hooman Kamran, Mohammad Hossein Anbardar, Mohammadreza Bordbar, Omid Reza Zekavat, Mehdi Forooghi
Format: Article
Language:English
Published: Karger Publishers 2023-09-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://beta.karger.com/Article/FullText/533829
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author Negar Safaei
Hooman Kamran
Mohammad Hossein Anbardar
Mohammadreza Bordbar
Omid Reza Zekavat
Mehdi Forooghi
author_facet Negar Safaei
Hooman Kamran
Mohammad Hossein Anbardar
Mohammadreza Bordbar
Omid Reza Zekavat
Mehdi Forooghi
author_sort Negar Safaei
collection DOAJ
description Teratoma is a type of germ cell tumor layer that appears in the gonadal, sacrococcygeal, mediastinal, and retroperitoneal regions. Primary retroperitoneal teratoma is rare and asymptomatic but can present with symptoms due to a mass effect on neighboring organs. These tumors have to be considered in the differential diagnosis of a mass in the abdominal cavity of children to distinguish between Wilms’ tumor, neuroblastoma, and other intra-abdominal lesions. We presented an infant boy with protrusion of the left upper quadrant of the abdomen and a palpable abdominal mass that had progressively enlarged. An abdominal computed tomography scan revealed a large retroperitoneal cystic, solid mass on the left side of the abdominal cavity, causing pressure on the left ureter. Also, hydronephrosis of the left kidney was seen with a decreased enhancement of the left kidney due to obstruction uropathy. The mass was suspicious on imaging for a retroperitoneal teratoma. The patient underwent laparotomy, and excision of the huge retroperitoneal mass was done. The final diagnosis was an immature teratoma grade 3, and the patient was discharged in good condition. Retroperitoneal teratomas are rare tumors in infants. These tumors would be an incident diagnosis or diagnosed by the mass effect of giant tumors on other organs. They must be considered in the differential diagnosis of intra-abdominal tumors in children. Hydronephrosis and obstructive uropathy can be rare consequences of the mass effects of these tumors.
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spelling doaj.art-785ea371d7294b93b602646ff871bd2e2023-10-26T06:38:32ZengKarger PublishersCase Reports in Oncology1662-65752023-09-011611041104710.1159/000533829533829Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the LiteratureNegar Safaei0Hooman Kamran1Mohammad Hossein Anbardar2Mohammadreza Bordbar3Omid Reza Zekavat4Mehdi Forooghi5Student Research Committee, Shiraz University of Medical Sciences, Shiraz, IranStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pathology, Shiraz University of Medical Sciences, Shiraz, IranHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IranHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pediatric Surgery, Shiraz University of Medical Sciences, Shiraz, IranTeratoma is a type of germ cell tumor layer that appears in the gonadal, sacrococcygeal, mediastinal, and retroperitoneal regions. Primary retroperitoneal teratoma is rare and asymptomatic but can present with symptoms due to a mass effect on neighboring organs. These tumors have to be considered in the differential diagnosis of a mass in the abdominal cavity of children to distinguish between Wilms’ tumor, neuroblastoma, and other intra-abdominal lesions. We presented an infant boy with protrusion of the left upper quadrant of the abdomen and a palpable abdominal mass that had progressively enlarged. An abdominal computed tomography scan revealed a large retroperitoneal cystic, solid mass on the left side of the abdominal cavity, causing pressure on the left ureter. Also, hydronephrosis of the left kidney was seen with a decreased enhancement of the left kidney due to obstruction uropathy. The mass was suspicious on imaging for a retroperitoneal teratoma. The patient underwent laparotomy, and excision of the huge retroperitoneal mass was done. The final diagnosis was an immature teratoma grade 3, and the patient was discharged in good condition. Retroperitoneal teratomas are rare tumors in infants. These tumors would be an incident diagnosis or diagnosed by the mass effect of giant tumors on other organs. They must be considered in the differential diagnosis of intra-abdominal tumors in children. Hydronephrosis and obstructive uropathy can be rare consequences of the mass effects of these tumors.https://beta.karger.com/Article/FullText/533829hydronephrosisimmature teratomaobstructive uropathyretroperitoneum spaceteratoma
spellingShingle Negar Safaei
Hooman Kamran
Mohammad Hossein Anbardar
Mohammadreza Bordbar
Omid Reza Zekavat
Mehdi Forooghi
Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature
Case Reports in Oncology
hydronephrosis
immature teratoma
obstructive uropathy
retroperitoneum space
teratoma
title Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature
title_full Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature
title_fullStr Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature
title_full_unstemmed Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature
title_short Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature
title_sort large retroperitoneal teratoma presenting with unilateral hydronephrosis in an infant a case report and review of the literature
topic hydronephrosis
immature teratoma
obstructive uropathy
retroperitoneum space
teratoma
url https://beta.karger.com/Article/FullText/533829
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