Comparison of methods for estimating the nucleotide substitution matrix

Comparison of methods for estimating the nucleotide substitution matrix

<p>Abstract</p> <p>Background</p> <p>The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different mathematical bases. These methods include counting sequence difference...

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Bibliographic Details
Main Authors:	Huttley Gavin A, Yap Von Bing, McDonald Daniel, Oscamou Maribeth, Lladser Manuel E, Knight Rob
Format:	Article
Language:	English
Published:	BMC 2008-12-01
Series:	BMC Bioinformatics
Online Access:	http://www.biomedcentral.com/1471-2105/9/511

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