Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma
Purpose: This study aimed to evaluate the prognostic factors affecting surgical outcomes, including visual acuity (VA) improvement, after glaucoma surgery in patients with neovascular glaucoma (NVG). Methods: The medical records of 116 patients (116 eyes) with NVG who had undergone trabeculectomy or...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-04-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024049697 |
| _version_ | 1797217105768087552 |
|---|---|
| author | Ji Hyoung Chey Chang Kyu Lee |
| author_facet | Ji Hyoung Chey Chang Kyu Lee |
| author_sort | Ji Hyoung Chey |
| collection | DOAJ |
| description | Purpose: This study aimed to evaluate the prognostic factors affecting surgical outcomes, including visual acuity (VA) improvement, after glaucoma surgery in patients with neovascular glaucoma (NVG). Methods: The medical records of 116 patients (116 eyes) with NVG who had undergone trabeculectomy or Ahmed glaucoma valve implantation were reviewed retrospectively. The primary outcome measure was surgical success at 6 postoperative months, defined as sufficient intraocular pressure (IOP) reduction (IOP ≤21 mmHg, ≥20% reduction, regardless of topical medication use) without additional glaucoma surgery, hypotony, or progression to no light perception. Success was categorized as complete or qualified based on whether an improvement in VA was observed in addition to the abovementioned definition. Results: The complete and qualified success rates at 6 months were 44.6% and 92.2%, respectively. Age (p = 0.001), preoperative best-corrected VA (p = 0.031), duration of decreased VA (p = 0.001), closed-angle status (p = 0.013), and etiology (p = 0.007) differed significantly between the groups with and without complete success. Multivariate analysis revealed that age (odds ratio [OR] 1.05; p = 0.026), duration of decreased VA (OR 1.05; p = 0.016), and 360° closed-angle status (OR 3.27; p = 0.031) were risk factors for surgical failure according to the complete success criteria, but not the qualified success criteria. Conclusions: Patients with NVG showed improved visual prognosis and successful IOP reduction after glaucoma surgery at a relatively younger age if the duration of visual loss was not prolonged and the angle status was not completely closed. |
| first_indexed | 2024-04-24T11:56:34Z |
| format | Article |
| id | doaj.art-786695173cbf4d3b9744ab70949394ab |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T11:56:34Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-786695173cbf4d3b9744ab70949394ab2024-04-09T04:13:22ZengElsevierHeliyon2405-84402024-04-01107e28938Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucomaJi Hyoung Chey0Chang Kyu Lee1Department of Ophthalmology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South KoreaDepartment of Ophthalmology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea; Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea; Corresponding author. Department of Ophthalmology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea.Purpose: This study aimed to evaluate the prognostic factors affecting surgical outcomes, including visual acuity (VA) improvement, after glaucoma surgery in patients with neovascular glaucoma (NVG). Methods: The medical records of 116 patients (116 eyes) with NVG who had undergone trabeculectomy or Ahmed glaucoma valve implantation were reviewed retrospectively. The primary outcome measure was surgical success at 6 postoperative months, defined as sufficient intraocular pressure (IOP) reduction (IOP ≤21 mmHg, ≥20% reduction, regardless of topical medication use) without additional glaucoma surgery, hypotony, or progression to no light perception. Success was categorized as complete or qualified based on whether an improvement in VA was observed in addition to the abovementioned definition. Results: The complete and qualified success rates at 6 months were 44.6% and 92.2%, respectively. Age (p = 0.001), preoperative best-corrected VA (p = 0.031), duration of decreased VA (p = 0.001), closed-angle status (p = 0.013), and etiology (p = 0.007) differed significantly between the groups with and without complete success. Multivariate analysis revealed that age (odds ratio [OR] 1.05; p = 0.026), duration of decreased VA (OR 1.05; p = 0.016), and 360° closed-angle status (OR 3.27; p = 0.031) were risk factors for surgical failure according to the complete success criteria, but not the qualified success criteria. Conclusions: Patients with NVG showed improved visual prognosis and successful IOP reduction after glaucoma surgery at a relatively younger age if the duration of visual loss was not prolonged and the angle status was not completely closed.http://www.sciencedirect.com/science/article/pii/S2405844024049697Neovascular glaucomaGlaucoma surgeryVisual improvementPrognostic factors |
| spellingShingle | Ji Hyoung Chey Chang Kyu Lee Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma Heliyon Neovascular glaucoma Glaucoma surgery Visual improvement Prognostic factors |
| title | Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma |
| title_full | Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma |
| title_fullStr | Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma |
| title_full_unstemmed | Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma |
| title_short | Surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma |
| title_sort | surgical outcomes including visual improvement after glaucoma surgery in patients with neovascular glaucoma |
| topic | Neovascular glaucoma Glaucoma surgery Visual improvement Prognostic factors |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024049697 |
| work_keys_str_mv | AT jihyoungchey surgicaloutcomesincludingvisualimprovementafterglaucomasurgeryinpatientswithneovascularglaucoma AT changkyulee surgicaloutcomesincludingvisualimprovementafterglaucomasurgeryinpatientswithneovascularglaucoma |