Screening drug target combinations in disease-related molecular networks

Abstract Background For treating a complex disease such as cancer, some effective means are needed to control biological networks that underlies the disease. The one-target one-drug paradigm has been the dominating drug discovery approach in the past decades. Compared to single target-based drugs, c...

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Bibliographic Details
Main Authors: Min Luo, Jianfeng Jiao, Ruiqi Wang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2730-8