Screening drug target combinations in disease-related molecular networks
Abstract Background For treating a complex disease such as cancer, some effective means are needed to control biological networks that underlies the disease. The one-target one-drug paradigm has been the dominating drug discovery approach in the past decades. Compared to single target-based drugs, c...
Main Authors: | Min Luo, Jianfeng Jiao, Ruiqi Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
|
Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-019-2730-8 |
Similar Items
-
Evaluation of synergism in drug combinations and reference models for future orientations in oncology
by: Diana Duarte, et al.
Published: (2022-01-01) -
Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergismsResearch in context
by: Jérémy Ariey-Bonnet, et al.
Published: (2023-09-01) -
Drug Combination in Cancer Treatment—From Cocktails to Conjugated Combinations
by: Yosi Gilad, et al.
Published: (2021-02-01) -
Integrated multiomic analysis and high‐throughput screening reveal potential gene targets and synergetic drug combinations for osteosarcoma therapy
by: Wenchao Zhang, et al.
Published: (2023-08-01) -
SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets
by: Shuyu Zheng, et al.
Published: (2022-06-01)