Influence of pre-pregnancy body mass index (p-BMI) and gestational weight gain (GWG) on DNA methylation and protein expression of obesogenic genes in umbilical vein.

Influence of pre-pregnancy body mass index (p-BMI) and gestational weight gain (GWG) on DNA methylation and protein expression of obesogenic genes in umbilical vein.

Understanding the regulatory mechanisms that affect obesogenic genes expression in newborns is essential for early prevention efforts, but they remain unclear. Our study aimed to explore whether the maternal p-BMI and GWG were associated with regulatory single-locus DNA methylation in selected obeso...

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Bibliographic Details
Main Authors: Erika Chavira-Suárez, Angélica Jazmín Ramírez-Mendieta, Sofía Martínez-Gutiérrez, Paola Zárate-Segura, Jorge Beltrán-Montoya, Nidia Carolina Espinosa-Maldonado, Juan Carlos de la Cerda-Ángeles, Felipe Vadillo-Ortega
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226010

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