Loss of CXC-Chemokine Receptor 1 Expression in Chorioamnionitis Is Associated with Adverse Perinatal Outcomes

Loss of CXC-Chemokine Receptor 1 Expression in Chorioamnionitis Is Associated with Adverse Perinatal Outcomes

Background: Chorioamnionitis complicates about 1–5% of deliveries at term and causes about one-third of stillbirths. CXC-chemokine receptor 1 (CXCR1) binds IL-8 with high affinity and regulates neutrophil recruitment. We aimed to determine the immunoexpression of CXCR1 in placentas with chorioamnion...

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Bibliographic Details
Main Authors: Yin Ping Wong, Noorhafizah Wagiman, Jonathan Wei De Tan, Barizah Syahirah Hanim, Muhammad Syamil Hilman Rashidan, Kai Mun Fong, Naufal Naqib Norhazli, Yashini Qrisha, Raja Norazah Raja Alam Shah, Muaatamarulain Mustangin, Haliza Zakaria, Siew Xian Chin, Geok Chin Tan
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Diagnostics
Subjects:
chorioamnionitis
CXCR1
interleukin-8
perinatal
placenta
Online Access:https://www.mdpi.com/2075-4418/12/4/882

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