The Preventive Mechanism of Anserine on Tert-Butyl Hydroperoxide-Induced Liver Injury in L-02 Cells via Regulating the Keap1-Nrf2 and JNK-Caspase-3 Signaling Pathways

The Preventive Mechanism of Anserine on Tert-Butyl Hydroperoxide-Induced Liver Injury in L-02 Cells via Regulating the Keap1-Nrf2 and JNK-Caspase-3 Signaling Pathways

Anserine is a naturally occurring histidine dipeptide with significant antioxidant activities. This study aimed to investigate the preventive mechanism of anserine on tert-butyl hydroperoxide (TBHP)-induced liver damage in a normal human liver cell line (L-02 cells). The L-02 cells were pretreated w...

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Bibliographic Details
Main Authors: Ming Chen, Jing Luo, Hongwu Ji, Wenkui Song, Di Zhang, Weiming Su, Shucheng Liu
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Marine Drugs
Subjects:
anrerine
liver injury
L-02 cell
oxidative stress
apoptosis
Keap1-Nrf2
Online Access:https://www.mdpi.com/1660-3397/21/9/477

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