Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is Gold
Pancreatic adenocarcinoma is the most common malignancy of the pancreas; on rare occasions, metastatic tumors are present. Differentiating a primary neoplasm from a metastatic one is important for ensuring adequate treatment for the patient. We present a case of metastatic melanoma to the pancreas....
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| Format: | Article |
| Language: | English |
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Karger Publishers
2021-02-01
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| Series: | Case Reports in Gastroenterology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/511864 |
| _version_ | 1818624197138579456 |
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| author | Jose Vargas-Jiménez Jorge Vargas-Madrigal Roberto Arias-Mora Diana Ulate-Ovares Bruno Solis-Ugalde |
| author_facet | Jose Vargas-Jiménez Jorge Vargas-Madrigal Roberto Arias-Mora Diana Ulate-Ovares Bruno Solis-Ugalde |
| author_sort | Jose Vargas-Jiménez |
| collection | DOAJ |
| description | Pancreatic adenocarcinoma is the most common malignancy of the pancreas; on rare occasions, metastatic tumors are present. Differentiating a primary neoplasm from a metastatic one is important for ensuring adequate treatment for the patient. We present a case of metastatic melanoma to the pancreas. A 60-year-old man presented with a history of weight loss, vague abdominal pain, jaundice, and pruritus. Laboratory tests showed increased total bilirubin, with a direct fraction predominance, as well as increased alkaline phosphatase and gamma glutamyl transferase. Imaging studies revealed a mass in the head of the pancreas. Endoscopic ultrasound (EUS)-guided fine needle biopsy was performed, and histologic examination confirmed the diagnosis of metastatic melanoma. This case report illustrates the invaluable use of EUS-guided tissue acquisition in the study of pancreatic solid lesions to obtain an accurate diagnosis. Melanomas should always be part of a differential diagnosis when evaluating patients with pancreatic masses. |
| first_indexed | 2024-12-16T18:53:07Z |
| format | Article |
| id | doaj.art-786f8395db994a10bdc5186dc223184b |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-16T18:53:07Z |
| publishDate | 2021-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-786f8395db994a10bdc5186dc223184b2022-12-21T22:20:38ZengKarger PublishersCase Reports in Gastroenterology1662-06312021-02-0115113113610.1159/000511864511864Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is GoldJose Vargas-JiménezJorge Vargas-MadrigalRoberto Arias-MoraDiana Ulate-OvaresBruno Solis-UgaldePancreatic adenocarcinoma is the most common malignancy of the pancreas; on rare occasions, metastatic tumors are present. Differentiating a primary neoplasm from a metastatic one is important for ensuring adequate treatment for the patient. We present a case of metastatic melanoma to the pancreas. A 60-year-old man presented with a history of weight loss, vague abdominal pain, jaundice, and pruritus. Laboratory tests showed increased total bilirubin, with a direct fraction predominance, as well as increased alkaline phosphatase and gamma glutamyl transferase. Imaging studies revealed a mass in the head of the pancreas. Endoscopic ultrasound (EUS)-guided fine needle biopsy was performed, and histologic examination confirmed the diagnosis of metastatic melanoma. This case report illustrates the invaluable use of EUS-guided tissue acquisition in the study of pancreatic solid lesions to obtain an accurate diagnosis. Melanomas should always be part of a differential diagnosis when evaluating patients with pancreatic masses.https://www.karger.com/Article/FullText/511864endoscopic ultrasoundmetastatic melanomapancreatic melanomaendoscopic ultrasound-guided fine needle biopsycase report |
| spellingShingle | Jose Vargas-Jiménez Jorge Vargas-Madrigal Roberto Arias-Mora Diana Ulate-Ovares Bruno Solis-Ugalde Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is Gold Case Reports in Gastroenterology endoscopic ultrasound metastatic melanoma pancreatic melanoma endoscopic ultrasound-guided fine needle biopsy case report |
| title | Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is Gold |
| title_full | Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is Gold |
| title_fullStr | Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is Gold |
| title_full_unstemmed | Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is Gold |
| title_short | Pancreatic Metastasis from Malignant Melanoma: Not All That Glitters Is Gold |
| title_sort | pancreatic metastasis from malignant melanoma not all that glitters is gold |
| topic | endoscopic ultrasound metastatic melanoma pancreatic melanoma endoscopic ultrasound-guided fine needle biopsy case report |
| url | https://www.karger.com/Article/FullText/511864 |
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