Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter
The ZIP family (SLC39A) is involved in transition metal homeostasis. Here, authors use integrated approaches to conclude that the ZIP from Bordetella bronchiseptica (BbZIP) utilizes the elevator-type transport mechanism to achieve alternating access.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-36048-4 |
| _version_ | 1811175819856314368 |
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| author | Yao Zhang Yuhan Jiang Kaifu Gao Dexin Sui Peixuan Yu Min Su Guo-Wei Wei Jian Hu |
| author_facet | Yao Zhang Yuhan Jiang Kaifu Gao Dexin Sui Peixuan Yu Min Su Guo-Wei Wei Jian Hu |
| author_sort | Yao Zhang |
| collection | DOAJ |
| description | The ZIP family (SLC39A) is involved in transition metal homeostasis. Here, authors use integrated approaches to conclude that the ZIP from Bordetella bronchiseptica (BbZIP) utilizes the elevator-type transport mechanism to achieve alternating access. |
| first_indexed | 2024-04-10T19:42:04Z |
| format | Article |
| id | doaj.art-786fffd65c6a4860b65cfd5b0e5f2c9f |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-10T19:42:04Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-786fffd65c6a4860b65cfd5b0e5f2c9f2023-01-29T12:16:29ZengNature PortfolioNature Communications2041-17232023-01-0114111410.1038/s41467-023-36048-4Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporterYao Zhang0Yuhan Jiang1Kaifu Gao2Dexin Sui3Peixuan Yu4Min Su5Guo-Wei Wei6Jian Hu7Department of Biochemistry and Molecular Biology, Michigan State UniversityDepartment of Chemistry, Michigan State UniversityDepartment of Mathematics, Michigan State UniversityDepartment of Biochemistry and Molecular Biology, Michigan State UniversityDepartment of Biochemistry and Molecular Biology, Michigan State UniversityLife Sciences Institute, University of MichiganDepartment of Biochemistry and Molecular Biology, Michigan State UniversityDepartment of Biochemistry and Molecular Biology, Michigan State UniversityThe ZIP family (SLC39A) is involved in transition metal homeostasis. Here, authors use integrated approaches to conclude that the ZIP from Bordetella bronchiseptica (BbZIP) utilizes the elevator-type transport mechanism to achieve alternating access.https://doi.org/10.1038/s41467-023-36048-4 |
| spellingShingle | Yao Zhang Yuhan Jiang Kaifu Gao Dexin Sui Peixuan Yu Min Su Guo-Wei Wei Jian Hu Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter Nature Communications |
| title | Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter |
| title_full | Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter |
| title_fullStr | Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter |
| title_full_unstemmed | Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter |
| title_short | Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter |
| title_sort | structural insights into the elevator type transport mechanism of a bacterial zip metal transporter |
| url | https://doi.org/10.1038/s41467-023-36048-4 |
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