Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two Cases

This article aims to prove dentin bridge formation in two cases after direct pulp capping in reversible pulpitis using the platelet concentrate A-PRF+ and preservation of the vitality of the dental pulp. The hemostasis process for the pulp wound and cavity disinfection with gaseous ozone was perform...

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Main Authors: Janet N. Kirilova, Dimitar Kosturkov
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/2/225
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author Janet N. Kirilova
Dimitar Kosturkov
author_facet Janet N. Kirilova
Dimitar Kosturkov
author_sort Janet N. Kirilova
collection DOAJ
description This article aims to prove dentin bridge formation in two cases after direct pulp capping in reversible pulpitis using the platelet concentrate A-PRF+ and preservation of the vitality of the dental pulp. The hemostasis process for the pulp wound and cavity disinfection with gaseous ozone was performed under anesthesia. A large A-PRF+ membrane was prepared from blood plasma and applied to the pulp wound. After placing an MTA, the cavity was closed using glass-ionomer cement. Clinical and cone beam computed tomography findings demonstrated the formation of a dentin bridge in both cases. After the definitive restoration was conducted during the sixth month, the teeth from both patients were asymptomatic and had normal electric pulp testing values. <i>Conclusions</i>: Via clinical and CBCT examinations, we observed the dentin bridge formation after placing the platelet concentrate A-PRF+ in both cases. The vitality of the dental pulp was preserved. Further research is needed to refine the clinical protocol, recommended period for control examination, clarification of the precise indications of platelet concentrates, etc.
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spelling doaj.art-7870b44fbfdd46fe9c2e8979bd7074742023-11-16T21:58:52ZengMDPI AGMedicina1010-660X1648-91442023-01-0159222510.3390/medicina59020225Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two CasesJanet N. Kirilova0Dimitar Kosturkov1Department of Conservative Dentistry, Faculty of Dental Medicine, Medical University, 1000 Sofia, BulgariaDepartment of Conservative Dentistry, Faculty of Dental Medicine, Medical University, 1000 Sofia, BulgariaThis article aims to prove dentin bridge formation in two cases after direct pulp capping in reversible pulpitis using the platelet concentrate A-PRF+ and preservation of the vitality of the dental pulp. The hemostasis process for the pulp wound and cavity disinfection with gaseous ozone was performed under anesthesia. A large A-PRF+ membrane was prepared from blood plasma and applied to the pulp wound. After placing an MTA, the cavity was closed using glass-ionomer cement. Clinical and cone beam computed tomography findings demonstrated the formation of a dentin bridge in both cases. After the definitive restoration was conducted during the sixth month, the teeth from both patients were asymptomatic and had normal electric pulp testing values. <i>Conclusions</i>: Via clinical and CBCT examinations, we observed the dentin bridge formation after placing the platelet concentrate A-PRF+ in both cases. The vitality of the dental pulp was preserved. Further research is needed to refine the clinical protocol, recommended period for control examination, clarification of the precise indications of platelet concentrates, etc.https://www.mdpi.com/1648-9144/59/2/225direct pulp cappingregenerative endodontic therapyplatelet-rich fibrinA-PRF+ozone therapy
spellingShingle Janet N. Kirilova
Dimitar Kosturkov
Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two Cases
Medicina
direct pulp capping
regenerative endodontic therapy
platelet-rich fibrin
A-PRF+
ozone therapy
title Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two Cases
title_full Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two Cases
title_fullStr Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two Cases
title_full_unstemmed Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two Cases
title_short Direct Pulp Capping with Advanced Platelet-Rich Fibrin: A Report of Two Cases
title_sort direct pulp capping with advanced platelet rich fibrin a report of two cases
topic direct pulp capping
regenerative endodontic therapy
platelet-rich fibrin
A-PRF+
ozone therapy
url https://www.mdpi.com/1648-9144/59/2/225
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