Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder
Methamphetamine use has become a rampant public health issue that not only causes devastating consequences to the user but also poses a burden to surrounding communities. A spectrum of ophthalmic sequelae is associated with methamphetamine use and includes episcleritis, scleritis, corneal ulceration...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Toxicology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/ftox.2023.1135792/full |
| _version_ | 1827996923946074112 |
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| author | Ye Huang Nam V. Nguyen Danny A. Mammo Thomas A. Albini Brent R. Hayek Brent D. Timperley Ronald R. Krueger Steven Yeh |
| author_facet | Ye Huang Nam V. Nguyen Danny A. Mammo Thomas A. Albini Brent R. Hayek Brent D. Timperley Ronald R. Krueger Steven Yeh |
| author_sort | Ye Huang |
| collection | DOAJ |
| description | Methamphetamine use has become a rampant public health issue that not only causes devastating consequences to the user but also poses a burden to surrounding communities. A spectrum of ophthalmic sequelae is associated with methamphetamine use and includes episcleritis, scleritis, corneal ulceration, panophthalmitis, endophthalmitis, retinal vasculitis, and retinopathy. In many instances, prompt recognition of the condition and associated infectious process and early initiation of antimicrobial therapy are crucial steps to preventing vision loss. In this review, we summarize the reported ocular complications that may result from methamphetamine use in addition to several postulated mechanisms regarding the ocular toxicity of methamphetamine. The increasing prevalence of methamphetamine use as a public health threat highlights the need for continued investigation of this ophthalmologic issue. |
| first_indexed | 2024-04-10T05:20:19Z |
| format | Article |
| id | doaj.art-7871c7eabdb2408a930cf4b0e6ed3c92 |
| institution | Directory Open Access Journal |
| issn | 2673-3080 |
| language | English |
| last_indexed | 2024-04-10T05:20:19Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Toxicology |
| spelling | doaj.art-7871c7eabdb2408a930cf4b0e6ed3c922023-03-08T09:32:00ZengFrontiers Media S.A.Frontiers in Toxicology2673-30802023-03-01510.3389/ftox.2023.11357921135792Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorderYe Huang0Nam V. Nguyen1Danny A. Mammo2Thomas A. Albini3Brent R. Hayek4Brent D. Timperley5Ronald R. Krueger6Steven Yeh7Department of Ophthalmology and Visual Sciences, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United StatesDepartment of Ophthalmology and Visual Sciences, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United StatesCleveland Clinic, Cole Eye Institute, Cleveland, OH, United StatesBascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, United StatesNorth Georgia Eye Clinic, Gainesville, GA, United StatesDepartment of Ophthalmology and Visual Sciences, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United StatesDepartment of Ophthalmology and Visual Sciences, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United StatesDepartment of Ophthalmology and Visual Sciences, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United StatesMethamphetamine use has become a rampant public health issue that not only causes devastating consequences to the user but also poses a burden to surrounding communities. A spectrum of ophthalmic sequelae is associated with methamphetamine use and includes episcleritis, scleritis, corneal ulceration, panophthalmitis, endophthalmitis, retinal vasculitis, and retinopathy. In many instances, prompt recognition of the condition and associated infectious process and early initiation of antimicrobial therapy are crucial steps to preventing vision loss. In this review, we summarize the reported ocular complications that may result from methamphetamine use in addition to several postulated mechanisms regarding the ocular toxicity of methamphetamine. The increasing prevalence of methamphetamine use as a public health threat highlights the need for continued investigation of this ophthalmologic issue.https://www.frontiersin.org/articles/10.3389/ftox.2023.1135792/fullmethamphetaminevision lossocular injurykeratitisneurotoxicityretinopathy |
| spellingShingle | Ye Huang Nam V. Nguyen Danny A. Mammo Thomas A. Albini Brent R. Hayek Brent D. Timperley Ronald R. Krueger Steven Yeh Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder Frontiers in Toxicology methamphetamine vision loss ocular injury keratitis neurotoxicity retinopathy |
| title | Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder |
| title_full | Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder |
| title_fullStr | Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder |
| title_full_unstemmed | Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder |
| title_short | Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder |
| title_sort | vision health perspectives on breaking bad ophthalmic sequelae of methamphetamine use disorder |
| topic | methamphetamine vision loss ocular injury keratitis neurotoxicity retinopathy |
| url | https://www.frontiersin.org/articles/10.3389/ftox.2023.1135792/full |
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