A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors
Objectives To explore the efficacy of microwave ablation (MWA) in the treatment of benign thyroid nodules, and analyze related influencing factors. Methods The clinical and ultrasound data of 115 patients with 115 benign thyroid nodules treated with MWA were retrospectively analyzed. The volume of n...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | http://dx.doi.org/10.1080/02656736.2021.1988151 |
| _version_ | 1818967583138775040 |
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| author | Qian-qian Fu Song Kang Cui-ping Wu Shi-yu Wang Ying-ying Liu Jia-wei Tian Shuang-quan Jiang |
| author_facet | Qian-qian Fu Song Kang Cui-ping Wu Shi-yu Wang Ying-ying Liu Jia-wei Tian Shuang-quan Jiang |
| author_sort | Qian-qian Fu |
| collection | DOAJ |
| description | Objectives To explore the efficacy of microwave ablation (MWA) in the treatment of benign thyroid nodules, and analyze related influencing factors. Methods The clinical and ultrasound data of 115 patients with 115 benign thyroid nodules treated with MWA were retrospectively analyzed. The volume of nodules at 1, 3, 6, and 12 months after the procedure was obtained, and the volume reduction rate (VRR) at each time point was calculated. With VRR > 90% as the criterion for nodule cure, binary logistic regression was employed to screen the factors that affect the efficacy. Results ① At 1, 3, 6, and 12 months after the procedure, the volume of nodules continued to decrease, the VRR gradually increased, and the differences at each time point were statistically significant (p < 0.05). A total of 29 (25.21%) nodules disappeared completely at 12 months after the procedure; ② Multivariate stepwise logistic regression showed that there was a statistically significant difference for the internal component of nodules, enhancement mode, and immediate volume after the procedure in determining the ablation efficacy (p < 0.05); ③ The ROC curve was plotted for predicting the efficacy of MWA, with the results showing that the AUC, sensitivity, specificity, and accuracy were 0.82, 67.50, 88.00, 79.10%, respectively; ④ 11 cases (9.56%) had side effects, 10 cases (8.70%) had minor complications, and three cases (2.61%) had major complications. Conclusion MWA is safe and effective in the treatment of benign thyroid nodules. The internal component of nodules, enhancement mode, and immediate volume after the procedure are independent factors that affect the efficacy of ablation. |
| first_indexed | 2024-12-20T13:51:06Z |
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| id | doaj.art-7874da9731414926a80c4b62d986b6d9 |
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| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-12-20T13:51:06Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-7874da9731414926a80c4b62d986b6d92022-12-21T19:38:31ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572021-01-013811469147510.1080/02656736.2021.19881511988151A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factorsQian-qian Fu0Song Kang1Cui-ping Wu2Shi-yu Wang3Ying-ying Liu4Jia-wei Tian5Shuang-quan Jiang6Department of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Harbin Medical UniversityObjectives To explore the efficacy of microwave ablation (MWA) in the treatment of benign thyroid nodules, and analyze related influencing factors. Methods The clinical and ultrasound data of 115 patients with 115 benign thyroid nodules treated with MWA were retrospectively analyzed. The volume of nodules at 1, 3, 6, and 12 months after the procedure was obtained, and the volume reduction rate (VRR) at each time point was calculated. With VRR > 90% as the criterion for nodule cure, binary logistic regression was employed to screen the factors that affect the efficacy. Results ① At 1, 3, 6, and 12 months after the procedure, the volume of nodules continued to decrease, the VRR gradually increased, and the differences at each time point were statistically significant (p < 0.05). A total of 29 (25.21%) nodules disappeared completely at 12 months after the procedure; ② Multivariate stepwise logistic regression showed that there was a statistically significant difference for the internal component of nodules, enhancement mode, and immediate volume after the procedure in determining the ablation efficacy (p < 0.05); ③ The ROC curve was plotted for predicting the efficacy of MWA, with the results showing that the AUC, sensitivity, specificity, and accuracy were 0.82, 67.50, 88.00, 79.10%, respectively; ④ 11 cases (9.56%) had side effects, 10 cases (8.70%) had minor complications, and three cases (2.61%) had major complications. Conclusion MWA is safe and effective in the treatment of benign thyroid nodules. The internal component of nodules, enhancement mode, and immediate volume after the procedure are independent factors that affect the efficacy of ablation.http://dx.doi.org/10.1080/02656736.2021.1988151benign thyroid nodulesmicrowave ablation (mwa)influencing factorsthermal ablationcontrast-enhanced ultrasound |
| spellingShingle | Qian-qian Fu Song Kang Cui-ping Wu Shi-yu Wang Ying-ying Liu Jia-wei Tian Shuang-quan Jiang A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors International Journal of Hyperthermia benign thyroid nodules microwave ablation (mwa) influencing factors thermal ablation contrast-enhanced ultrasound |
| title | A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors |
| title_full | A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors |
| title_fullStr | A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors |
| title_full_unstemmed | A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors |
| title_short | A study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors |
| title_sort | study on the efficacy of microwave ablation for benign thyroid nodules and related influencing factors |
| topic | benign thyroid nodules microwave ablation (mwa) influencing factors thermal ablation contrast-enhanced ultrasound |
| url | http://dx.doi.org/10.1080/02656736.2021.1988151 |
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