CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury

CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury

AKI, due to the fact of altered oxygen supply after kidney transplantation, is characterized by renal ischemia–reperfusion injury (IRI). Recent data suggest that AKI to CKD progression may be driven by cellular senescence evolving from prolonged DNA damage response (DDR) following oxidative stress....

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Bibliografiska uppgifter
Huvudupphovsmän: Floris A. Valentijn, Sebastiaan N. Knoppert, Georgios Pissas, Raúl R. Rodrigues-Diez, Laura Marquez-Exposito, Roel Broekhuizen, Michal Mokry, Lennart A. Kester, Lucas L. Falke, Roel Goldschmeding, Marta Ruiz-Ortega, Theodoros Eleftheriadis, Tri Q. Nguyen
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2021-12-01
Serie:Antioxidants
Ämnen:
acute kidney injury
ischemia–reperfusion injury
oxidative stress response
DNA damage response
cell cycle arrest
cellular communication network factor 2
Länkar:https://www.mdpi.com/2076-3921/10/12/2020

Internet

https://www.mdpi.com/2076-3921/10/12/2020

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