Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation
Many stem cells exhibit cell division coupled to differentiation, though the changes occurring between consecutive cell divisions have been difficult to study. Here they use synchronized hPSC culture to show that production of transcription factors and epigenetic changes are linked with cell divisio...
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Bibliographic Details
| Main Authors: |
Pedro Madrigal,
Siwei Deng,
Yuliang Feng,
Stefania Militi,
Kim Jee Goh,
Reshma Nibhani,
Rodrigo Grandy,
Anna Osnato,
Daniel Ortmann,
Stephanie Brown,
Siim Pauklin |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-023-36116-9
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