Gray matter volume reduction in orbitofrontal cortex correlated with plasma glial cell line-derived neurotrophic factor (GDNF) levels within major depressive disorder

Gray matter volume reduction in orbitofrontal cortex correlated with plasma glial cell line-derived neurotrophic factor (GDNF) levels within major depressive disorder

Background: Major depressive disorder (MDD) is a severe mental disorder characterized by reduced gray matter volume (GMV). To date, the pathogenesis of MDD remains unclear, but neurotrophic factors play an essential role in the pathophysiological alterations of MDD during disease development. In par...

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Bibliographic Details
Main Authors: Yifan Wu, Lingtao Kong, Anqi Yang, Kaiqi Xin, Yihui Lu, Xintong Yan, Wen Liu, Yue Zhu, Yingrui Guo, Xiaowei Jiang, Yifang Zhou, Qikun Sun, Yanqing Tang, Feng Wu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Gray matter volume
GDNF
Major depressive disorder
Neuroimaging
Orbitofrontal cortex
Online Access:http://www.sciencedirect.com/science/article/pii/S221315822300030X

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