Involvement of the ABCB1 C3435T Variant but Not the MTHFR C677T or MTHFR A1298C Variant in High-Dose Methotrexate-Induced Toxicity in Pediatric Acute Lymphoblastic Leukemia Patients in China

Involvement of the ABCB1 C3435T Variant but Not the MTHFR C677T or MTHFR A1298C Variant in High-Dose Methotrexate-Induced Toxicity in Pediatric Acute Lymphoblastic Leukemia Patients in China

Qie Guo,1 Jia-Lin Sun,1 Ran Li,2 Xiao Li1 1Department of Clinical Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 2Department of Infectious Diseases, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of ChinaCo...

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Bibliographic Details
Main Authors: Guo Q, Sun JL, Li R, Li X
Format: Article
Language:English
Published: Dove Medical Press 2024-03-01
Series:International Journal of General Medicine
Subjects:
high-dose methotrexate toxicities
mthfr c677t and mthfr a1298c genetic variants
abcb1 c3435t genetic variant
mtx elimination delay
acute lymphoblastic leukemia
Online Access:https://www.dovepress.com/involvement-of-the-abcb1-c3435t-variant-but-not-the-mthfr-c677t-or-mth-peer-reviewed-fulltext-article-IJGM

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https://www.dovepress.com/involvement-of-the-abcb1-c3435t-variant-but-not-the-mthfr-c677t-or-mth-peer-reviewed-fulltext-article-IJGM

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