Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial
<h4>Introduction</h4> Peripheral artery disease and cardiac disease are often comorbid conditions. Echocardiography is a diagnostic tool that can be performed preoperatively to risk stratify patients by a functional cardiac test. We hypothesized that ventricular dysfunction and valvular...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851553/?tool=EBI |
| _version_ | 1797943923689127936 |
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| author | Matthew J. Meyer Slater A. Jameson Edward J. Gillig Ankur Aggarwal Sarah J. Ratcliffe Mary Baldwin Karen E. Singh W. Darrin Clouse Randal S. Blank |
| author_facet | Matthew J. Meyer Slater A. Jameson Edward J. Gillig Ankur Aggarwal Sarah J. Ratcliffe Mary Baldwin Karen E. Singh W. Darrin Clouse Randal S. Blank |
| author_sort | Matthew J. Meyer |
| collection | DOAJ |
| description | <h4>Introduction</h4> Peripheral artery disease and cardiac disease are often comorbid conditions. Echocardiography is a diagnostic tool that can be performed preoperatively to risk stratify patients by a functional cardiac test. We hypothesized that ventricular dysfunction and valvular lesions were associated with an increased incidence of expanded major adverse cardiac events (Expanded MACE). <h4>Methods and materials</h4> Retrospective cohort study from 2011 to 2020 including all patients from a major academic center who had vascular surgery and an echocardiographic study within two years of the index procedure. <h4>Results</h4> 813 patients were included in the study; a majority had a history of smoking (86%), an ASA score of 3 (65%), and were male (68%). Carotid endarterectomy was the most common surgery (24%) and the least common surgery was open abdominal aortic aneurysm repair (5%). We found no significant association between the echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction, or valvular lesions and the postoperative development of Expanded MACE. <h4>Conclusions</h4> The preoperative echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction and moderate to severe valvular lesions were not predictive of an increased incidence of postoperative Expanded MACE. We identified a significant association between RV dysfunction and post-operative dialysis that should be interpreted carefully due to the small number of outcomes. The transition from open to endovascular surgery and advances in perioperative management may have led to improved cardiovascular outcomes. <h4>Trial registration</h4> Trial Registration:NCT04836702 (clinicaltrials.gov). https://www.google.com/search?client=firefox-b-d&q=NCT04836702. |
| first_indexed | 2024-04-10T20:31:47Z |
| format | Article |
| id | doaj.art-78807b34bafd4b319d9c45b9453419f3 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-10T20:31:47Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-78807b34bafd4b319d9c45b9453419f32023-01-25T05:33:52ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01181Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trialMatthew J. MeyerSlater A. JamesonEdward J. GilligAnkur AggarwalSarah J. RatcliffeMary BaldwinKaren E. SinghW. Darrin ClouseRandal S. Blank<h4>Introduction</h4> Peripheral artery disease and cardiac disease are often comorbid conditions. Echocardiography is a diagnostic tool that can be performed preoperatively to risk stratify patients by a functional cardiac test. We hypothesized that ventricular dysfunction and valvular lesions were associated with an increased incidence of expanded major adverse cardiac events (Expanded MACE). <h4>Methods and materials</h4> Retrospective cohort study from 2011 to 2020 including all patients from a major academic center who had vascular surgery and an echocardiographic study within two years of the index procedure. <h4>Results</h4> 813 patients were included in the study; a majority had a history of smoking (86%), an ASA score of 3 (65%), and were male (68%). Carotid endarterectomy was the most common surgery (24%) and the least common surgery was open abdominal aortic aneurysm repair (5%). We found no significant association between the echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction, or valvular lesions and the postoperative development of Expanded MACE. <h4>Conclusions</h4> The preoperative echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction and moderate to severe valvular lesions were not predictive of an increased incidence of postoperative Expanded MACE. We identified a significant association between RV dysfunction and post-operative dialysis that should be interpreted carefully due to the small number of outcomes. The transition from open to endovascular surgery and advances in perioperative management may have led to improved cardiovascular outcomes. <h4>Trial registration</h4> Trial Registration:NCT04836702 (clinicaltrials.gov). https://www.google.com/search?client=firefox-b-d&q=NCT04836702.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851553/?tool=EBI |
| spellingShingle | Matthew J. Meyer Slater A. Jameson Edward J. Gillig Ankur Aggarwal Sarah J. Ratcliffe Mary Baldwin Karen E. Singh W. Darrin Clouse Randal S. Blank Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial PLoS ONE |
| title | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
| title_full | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
| title_fullStr | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
| title_full_unstemmed | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
| title_short | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
| title_sort | clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery an observational trial |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851553/?tool=EBI |
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