Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip Artroplasty

Background: One of the most important complications of immobilization is deep vein thrombosis (DVT), especially in lower extremities, and major surgeries, especially orthopaedic surgery. The aim of this study was comparing the effectiveness of heparin among short-time (10 days) and long-time (20 day...

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Main Authors: Hamidreza Arti, Reza Rouzbahani
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2013-06-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/2682
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author Hamidreza Arti
Reza Rouzbahani
author_facet Hamidreza Arti
Reza Rouzbahani
author_sort Hamidreza Arti
collection DOAJ
description Background: One of the most important complications of immobilization is deep vein thrombosis (DVT), especially in lower extremities, and major surgeries, especially orthopaedic surgery. The aim of this study was comparing the effectiveness of heparin among short-time (10 days) and long-time (20 days) enoxaparine administration to introdue more suitable preventive method. Methods: In a prospective study, 120 patients underwent hip arthroplasty enrolled in three groups; group I recieved 5000 IU heparin three times daily (ter die sumendum or TDS), Group II recieved 40 mg enoxaparine daily for 10 days, and Group III received 40 mg enoxaparine daily for 20 days. After data collection by check list, the ANOVA and χ2 tests were used for analysis. P-value less than 0.05 was considered significant. Findings: Incidence of deep vein thrombosis in group III was reduced more than group I after hip replacement surgery. Also, pulmonary thromboembolism (PTE) was reduced in group III more than group II. PTE and postoperative death were not significantly different among enoxaparin and heparin groups. Conclusion: Enoxaparin is more effective than standard heparin in reducing pulmonary thromboembolism and deep vein thrombosis.
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spelling doaj.art-7886724aa46a474c80971a09e959c3752023-09-02T19:00:04ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2013-06-01312313813881308Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip ArtroplastyHamidreza Arti0Reza Rouzbahani1Associate Professor, Department of Orthopedic Surgery, School of Medicine, Jundishapour University of Medical Sciences, Ahvaz, IranSpecialist in Community Medicine, Researcher, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranBackground: One of the most important complications of immobilization is deep vein thrombosis (DVT), especially in lower extremities, and major surgeries, especially orthopaedic surgery. The aim of this study was comparing the effectiveness of heparin among short-time (10 days) and long-time (20 days) enoxaparine administration to introdue more suitable preventive method. Methods: In a prospective study, 120 patients underwent hip arthroplasty enrolled in three groups; group I recieved 5000 IU heparin three times daily (ter die sumendum or TDS), Group II recieved 40 mg enoxaparine daily for 10 days, and Group III received 40 mg enoxaparine daily for 20 days. After data collection by check list, the ANOVA and χ2 tests were used for analysis. P-value less than 0.05 was considered significant. Findings: Incidence of deep vein thrombosis in group III was reduced more than group I after hip replacement surgery. Also, pulmonary thromboembolism (PTE) was reduced in group III more than group II. PTE and postoperative death were not significantly different among enoxaparin and heparin groups. Conclusion: Enoxaparin is more effective than standard heparin in reducing pulmonary thromboembolism and deep vein thrombosis.http://jims.mui.ac.ir/index.php/jims/article/view/2682Deep vein thrombosis (DVT)Pulmonary thrombo embolism (PTE)HeparinEnoxaparin
spellingShingle Hamidreza Arti
Reza Rouzbahani
Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip Artroplasty
مجله دانشکده پزشکی اصفهان
Deep vein thrombosis (DVT)
Pulmonary thrombo embolism (PTE)
Heparin
Enoxaparin
title Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip Artroplasty
title_full Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip Artroplasty
title_fullStr Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip Artroplasty
title_full_unstemmed Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip Artroplasty
title_short Comparing the Effectiveness Results of Heparin and Enoxaparin after Total Hip Artroplasty
title_sort comparing the effectiveness results of heparin and enoxaparin after total hip artroplasty
topic Deep vein thrombosis (DVT)
Pulmonary thrombo embolism (PTE)
Heparin
Enoxaparin
url http://jims.mui.ac.ir/index.php/jims/article/view/2682
work_keys_str_mv AT hamidrezaarti comparingtheeffectivenessresultsofheparinandenoxaparinaftertotalhipartroplasty
AT rezarouzbahani comparingtheeffectivenessresultsofheparinandenoxaparinaftertotalhipartroplasty