DNA Methylation-Based Age Prediction and Telomere Length Reveal an Accelerated Aging in Induced Sputum Cells Compared to Blood Leukocytes: A Pilot Study in COPD Patients

DNA Methylation-Based Age Prediction and Telomere Length Reveal an Accelerated Aging in Induced Sputum Cells Compared to Blood Leukocytes: A Pilot Study in COPD Patients

Aging is the predominant risk factor for most degenerative diseases, including chronic obstructive pulmonary disease (COPD). This process is however very heterogeneous. Defining the biological aging of individual tissues may contribute to better assess this risky process. In this study, we examined...

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Bibliographic Details
Main Authors: Manuela Campisi, Filippo Liviero, Piero Maestrelli, Gabriella Guarnieri, Sofia Pavanello
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Medicine
Subjects:
DNA methylation age
age acceleration
induced sputum
chronic obstructive pulmonary disease
lung aging
telomere length
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.690312/full

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