Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved?
The majority of Bt maize production in the European Union (EU) is concentrated in northeast Spain, which is Europe's only hotspot where resistance might evolve, and the main target pest, Sesamia nonagrioides, has been exposed to Cry1Ab maize continuously since 1998. The cropping system in north...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4856266?pdf=render |
| _version_ | 1819064682817781760 |
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| author | Pedro Castañera Gema P Farinós Félix Ortego David A Andow |
| author_facet | Pedro Castañera Gema P Farinós Félix Ortego David A Andow |
| author_sort | Pedro Castañera |
| collection | DOAJ |
| description | The majority of Bt maize production in the European Union (EU) is concentrated in northeast Spain, which is Europe's only hotspot where resistance might evolve, and the main target pest, Sesamia nonagrioides, has been exposed to Cry1Ab maize continuously since 1998. The cropping system in northeast Spain has some similar characteristics to those that probably led to rapid resistance failures in two other target noctuid maize pests. These include repeated cultivation of Bt maize in the same fields, low use of refuges, recurring exposure of larvae to non-high dose concentrations of Cry1Ab toxin during the first years of cultivation, low migratory potential, and production concentrated in an irrigated region with few alternative hosts. Available data reveal no evidence of resistance in S. nonagrioides after 16 years of use. We explore the possible reasons for this resistance management success using evolutionary models to consider factors expected to accelerate resistance, and those expected to delay resistance. Low initial adoption rates and the EU policy decision to replace Event 176 with MON 810 Bt maize were key to delaying resistance evolution. Model results suggest that if refuge compliance continues at the present 90%, Bt maize might be used sustainably in northeast Spain for at least 20 more years before resistance might occur. However, obtaining good estimates of the present R allele frequency and level of local assortative mating are crucial to reduce uncertainty about the future success of resistance management. |
| first_indexed | 2024-12-21T15:34:27Z |
| format | Article |
| id | doaj.art-78920c84f7884cefb83eef780f909229 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T15:34:27Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-78920c84f7884cefb83eef780f9092292022-12-21T18:58:40ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01115e015420010.1371/journal.pone.0154200Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved?Pedro CastañeraGema P FarinósFélix OrtegoDavid A AndowThe majority of Bt maize production in the European Union (EU) is concentrated in northeast Spain, which is Europe's only hotspot where resistance might evolve, and the main target pest, Sesamia nonagrioides, has been exposed to Cry1Ab maize continuously since 1998. The cropping system in northeast Spain has some similar characteristics to those that probably led to rapid resistance failures in two other target noctuid maize pests. These include repeated cultivation of Bt maize in the same fields, low use of refuges, recurring exposure of larvae to non-high dose concentrations of Cry1Ab toxin during the first years of cultivation, low migratory potential, and production concentrated in an irrigated region with few alternative hosts. Available data reveal no evidence of resistance in S. nonagrioides after 16 years of use. We explore the possible reasons for this resistance management success using evolutionary models to consider factors expected to accelerate resistance, and those expected to delay resistance. Low initial adoption rates and the EU policy decision to replace Event 176 with MON 810 Bt maize were key to delaying resistance evolution. Model results suggest that if refuge compliance continues at the present 90%, Bt maize might be used sustainably in northeast Spain for at least 20 more years before resistance might occur. However, obtaining good estimates of the present R allele frequency and level of local assortative mating are crucial to reduce uncertainty about the future success of resistance management.http://europepmc.org/articles/PMC4856266?pdf=render |
| spellingShingle | Pedro Castañera Gema P Farinós Félix Ortego David A Andow Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved? PLoS ONE |
| title | Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved? |
| title_full | Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved? |
| title_fullStr | Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved? |
| title_full_unstemmed | Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved? |
| title_short | Sixteen Years of Bt Maize in the EU Hotspot: Why Has Resistance Not Evolved? |
| title_sort | sixteen years of bt maize in the eu hotspot why has resistance not evolved |
| url | http://europepmc.org/articles/PMC4856266?pdf=render |
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